Diabetes mellitus and oral mucosa alterations: Prevalence and risk factors

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dc.contributor.authorBastos, Alliny de Souza [UNESP]
dc.contributor.authorPerin Leite, Andressa Rosa [UNESP]
dc.contributor.authorSpin-Neto, Rubens [UNESP]
dc.contributor.authorNassar, Patricia Oehlmeyer
dc.contributor.authorMassucato, Elaine Maria Sgavioli [UNESP]
dc.contributor.authorOrrico, Silvana Regina Perez [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Estadual do Oeste do Paraná (UNIOESTE)
dc.date.accessioned2013-09-30T18:31:48Z
dc.date.accessioned2014-05-20T13:45:23Z
dc.date.available2013-09-30T18:31:48Z
dc.date.available2014-05-20T13:45:23Z
dc.date.issued2011-04-01
dc.description.abstractAims: To investigate the prevalence of oral mucosa alterations in patients with type 2 diabetes and to identify possible risk factors related to oral mucosa alterations.Methods: 146 patients with type 2 diabetes and 111 age-and gender-matched healthy controls subjects were consecutively recruited from Araraquara School of Dentistry to answer a structured questionnaire designed to collect demographic data as well as current and former history of diabetes. Clinical examination of the oral mucosa was carried out by a stomatologist.Results: A higher prevalence of oral mucosa alterations was found in patients with diabetes than in patients without diabetes (p < 0.001), with significant difference to development conditions (p < 0.0001), potentially malignant disorders (p < 0.0001) and fungal infections (p < 0.05). In the multiple logistic regression, diabetes (odds ratio 9.9 IC 5.11-19.16) and smoking habit (odds ratio 3.17 IC 1.42-7.12) increased the odds of oral mucosa alterations significantly.Conclusions: Patients with diabetes mellitus not only showed an increased prevalence of oral mucosa alterations but also a significant percentage of potentially malignant disorders. These findings elucidate the necessity of regular clinical examination to ensure early diagnosis and prompt management of oral mucosa lesions in patients with diabetes. (C) 2011 Elsevier B.V. All rights reserved.en
dc.description.affiliationUniv Estadual Paulista, Araraquara Sch Dent, Dept Diag & Surg, UNESP, BR-14801903 São Paulo, Brazil
dc.description.affiliationUNIOESTE Univ State W Parana, Dept Periodontoloy, Cascavel Dent Sch, Cascavel, Parana, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Araraquara Sch Dent, Dept Diag & Surg, UNESP, BR-14801903 São Paulo, Brazil
dc.format.extent100-105
dc.identifierhttp://dx.doi.org/10.1016/j.diabres.2011.01.011
dc.identifier.citationDiabetes Research and Clinical Practice. Clare: Elsevier B.V., v. 92, n. 1, p. 100-105, 2011.
dc.identifier.doi10.1016/j.diabres.2011.01.011
dc.identifier.issn0168-8227
dc.identifier.lattes7383391319292040
dc.identifier.urihttp://hdl.handle.net/11449/15962
dc.identifier.wosWOS:000289558300023
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofDiabetes Research and Clinical Practice
dc.relation.ispartofjcr2.548
dc.relation.ispartofsjr1,538
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectDiabetes mellitusen
dc.subjectDiagnosisen
dc.subjectPrevalenceen
dc.subjectMucosaen
dc.subjectOral pathologyen
dc.titleDiabetes mellitus and oral mucosa alterations: Prevalence and risk factorsen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderElsevier B.V.
unesp.author.lattes7383391319292040
unesp.author.orcid0000-0002-3703-2714[2]
unesp.author.orcid0000-0002-9562-0610[3]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araraquarapt

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