Avaliação da fertilidade e de possíveis defeitos estruturais externos sobre a prole de ratos machos expostos cronicamente ao arsênio

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dc.contributor.authorOliveira, Rodrigo Juliano [UNESP]
dc.contributor.authorOliva, Samara U.
dc.contributor.authorDaroz, Gisela A. [UNESP]
dc.contributor.authorRúbio, Eliana M. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Estadual de Londrina (UEL)
dc.contributor.institutionEdificio Portal Versalhes I
dc.date.accessioned2014-05-27T11:21:21Z
dc.date.available2014-05-27T11:21:21Z
dc.date.issued2005-06-01
dc.description.abstractArsenic is an environmental pollutant that influences the male reproductive function, affecting the spermatogenesis process in the testis and causing alterations in the sperm. The objective of this work was evaluate the reproductive efficiency in adult male rats exposed to arsenic and the possible male-mediated structural malformations. The animal were treated with sodium arsenato (3,6 mg/Kg, i.p.), twice a weak, for 15, 30, 45, 60 or 75 days whereas control received only distilled water. Results have showed a reduced pregnancy rate associated to a decrease in the fertility potencial and to a increase in the preimplantation loss. There was a decrease in the fetal weights, as showed by its average. Malformations rate, postimplantation loss and resorptions were unaffect by treatment. These results suggest that chronic exposure to arsenic provokes reduction on fertility of male rats. Further studies are required to clarify the arsenic effects on male reproductive system and male-mediated effects on progeny.en
dc.description.affiliationDepartamento de Urologia Faculdade de Medicina de Botucatu
dc.description.affiliationDepartamento de Morfologia Universidade Estadual de Londrina
dc.description.affiliationEdificio Portal Versalhes I, Rua Augusto Guerino, n 195, CEP 86067-200 - Londrina - PR
dc.description.affiliationUnespDepartamento de Urologia Faculdade de Medicina de Botucatu
dc.format.extent57-61
dc.identifier.citationRevista Brasileira de Toxicologia, v. 18, n. 1, p. 57-61, 2005.
dc.identifier.issn1415-2983
dc.identifier.scopus2-s2.0-27844448078
dc.identifier.urihttp://hdl.handle.net/11449/68272
dc.language.isopor
dc.relation.ispartofRevista Brasileira de Toxicologia
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectArsenic
dc.subjectFertility
dc.subjectMalformation
dc.subjectProgeny
dc.subjectRats
dc.subjectReproductive effects
dc.subjectarsenate sodium
dc.subjectarsenic
dc.subjectwater
dc.subjectconference paper
dc.subjectcongenital malformation
dc.subjectcontrolled study
dc.subjectembryo resorption
dc.subjectfetus weight
dc.subjectlong term exposure
dc.subjectmale
dc.subjectmale fertility
dc.subjectnidation
dc.subjectnonhuman
dc.subjectpollution
dc.subjectpregnancy rate
dc.subjectpreimplantation embryo
dc.subjectprogeny
dc.subjectrat
dc.subjectreproductive effort
dc.subjectsubfertility
dc.subjectAnimalia
dc.titleAvaliação da fertilidade e de possíveis defeitos estruturais externos sobre a prole de ratos machos expostos cronicamente ao arsêniopt
dc.title.alternativeFertility assessment and possible external structural defects on progeny from male rats chronically exposed to arsenicen
dc.typeTrabalho apresentado em evento
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

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