Platelet-rich plasma (PRP): methodological aspects and clinical applications

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dc.contributor.authorMarques, Laís Fernanda [UNESP]
dc.contributor.authorStessuk, Talita
dc.contributor.authorCamargo, Isabel Cristina Cherici [UNESP]
dc.contributor.authorSabeh Junior, Nemi
dc.contributor.authorSantos, Lucinéia dos [UNESP]
dc.contributor.authorPaes, João Tadeu Ribeiro [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2015-08-21T17:53:27Z
dc.date.available2015-08-21T17:53:27Z
dc.date.issued2014
dc.description.abstractThe clinical use of platelet-rich plasma (PRP) is based on the increase in the concentration of growth factors and in the secretion of proteins which are able to maximize the healing process at the cellular level. Since PRP is an autologous biologic material, it involves a minimum risk of immune reactions and transmission of infectious and contagious diseases, and it has been widely used for the recovery of musculoskeletal lesions. Despite the great potential for applicability, the implementation of the therapeutic employment of PRP as a clinical alternative has become difficult, due to the lack of studies related to the standardization of the techniques and/or insufficient description of the adopted procedures. Therefore, it is required establish standard criteria to be followed for obtaining a PRP of high quality, as well as a larger number of studies which should establish the proper concentration of platelets for the different clinical conditions. In this context, the purpose of this review is to discuss some methodological aspects used for achieving the PRP, as well as to discuss the bioactive properties of PRP, and to point out its therapeutic use in different fields of regenerative medicine.en
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Ciencias Biologicas, Faculdade de Ciências e Letras de Assis, Assis, Av. Dom Antonio, 2100, Parque Universitário, CEP 19806-900, SP, Brasil
dc.format.extent101-113
dc.identifierhttp://www.tandfonline.com/doi/full/10.3109/09537104.2014.881991#.Vc5CY_lViko
dc.identifier.citationPlatelets, v. 26, n. 2, p. 101-113, 2014.
dc.identifier.doi10.3109/09537104.2014.881991
dc.identifier.issn1369-1635
dc.identifier.lattes1126105849856055
dc.identifier.lattes2620573504503756
dc.identifier.urihttp://hdl.handle.net/11449/126912
dc.language.isoeng
dc.relation.ispartofPlatelets
dc.relation.ispartofsjr0,721
dc.rights.accessRightsAcesso restrito
dc.sourceCurrículo Lattes
dc.subjectBoneen
dc.subjectCartilageen
dc.subjectMuscleen
dc.subjectPlatelet-richen
dc.subjectPlasmaen
dc.subjectTendonen
dc.titlePlatelet-rich plasma (PRP): methodological aspects and clinical applicationsen
dc.typeArtigo
unesp.author.lattes1126105849856055
unesp.author.lattes2620573504503756[5]
unesp.author.orcid0000-0002-2826-2622[5]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências e Letras, Assispt
unesp.departmentCiências Biológicaspt

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Artigos - Ciências Biológicas - FCLAS