A pro-inflammatory role of lymphoid cells in acute pleurisy in rats

Página do item simplificado
dc.contributor.authorBechara, G. H.
dc.contributor.authorBates, M. B.
dc.contributor.authorDunn, C. J.
dc.contributor.authorWilloughby, D. A.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T01:31:02Z
dc.date.available2014-05-27T01:31:02Z
dc.date.issued1986-01-01
dc.description.abstractThe effect of viable splenic lymphoid cells and their constituents (filtrate) on carrageenan-induced acute pleurisy was investigated in rats. Suspensions of lymphoid cells administered intravenously to recipients just prior to initiation of pleurisy enhance both the volume of exudate and cell accumulation in the pleural cavity 3 h after the irritation. Similar results were observed when filtrate of disrupted lymphoid cells was injected either 30 or 5 min before the carrageenan, but not when administered 30 min afterwards. Suspensions of bone marrow cells, on the contrary, were ineffective in producing an enhancement of the parameters studied. When administered into the pleural cavity together with carrageenan, the lymphoid cell filtrate augmented the inflammatory response to the irritant. Nevertheless, it was ineffective, per se, to elicit any local change. It is suggested that lymphoid cells may play a pro-inflammatory role in the initiation of the process by enhancing both the fluid and the cellular components of inflammation.en
dc.format.extent419-422
dc.identifierhttp://dx.doi.org/10.1159/000234012
dc.identifier.citationInternational Archives of Allergy and Applied Immunology, v. 79, n. 4, p. 419-422, 1986.
dc.identifier.doi10.1159/000234012
dc.identifier.issn0020-5915
dc.identifier.lattes2382374201685423
dc.identifier.scopus2-s2.0-0022591346
dc.identifier.urihttp://hdl.handle.net/11449/63762
dc.language.isoeng
dc.relation.ispartofInternational Archives of Allergy and Applied Immunology
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectcarrageenan
dc.subjectanimal experiment
dc.subjectinflammation
dc.subjectlymphocytic infiltration
dc.subjectnonhuman
dc.subjectpleurisy
dc.subjectpriority journal
dc.subjectrat
dc.subjectrespiratory system
dc.subjectAcute Disease
dc.subjectAnimal
dc.subjectImmunization, Passive
dc.subjectInjections
dc.subjectLymphoid Tissue
dc.subjectMale
dc.subjectPleura
dc.subjectPleurisy
dc.subjectRats
dc.subjectRats, Inbred Strains
dc.subjectSupport, Non-U.S. Gov't
dc.titleA pro-inflammatory role of lymphoid cells in acute pleurisy in ratsen
dc.typeArtigo
dcterms.licensehttp://www.karger.com/Services/RightsPermissions
unesp.author.lattes2382374201685423
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Agrárias e Veterinárias, Jaboticabalpt

Arquivos

Coleções

Artigos - Patologia Veterinária - FCAV