Enamel matrix protein derivative plus synthetic bone substitute for the treatment of mandibular Class II furcation defects: a case series

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dc.contributor.authorQueiroz, Lucas Araujo
dc.contributor.authorSantamaria, Mauro Pedrine [UNESP]
dc.contributor.authorCasati, Marcio
dc.contributor.authorSilverio, Karina
dc.contributor.authorNociti Junior, Francisco
dc.contributor.authorSallum, Enilson
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2015-10-22T06:37:50Z
dc.date.available2015-10-22T06:37:50Z
dc.date.issued2015-03-01
dc.description.abstractObjectives: The aim of this study is to report on the treatment of mandibular Class II furcation defects with enamel matrix protein derivative (EMD) combined with a beta TCP/HA (beta-tricalcium phosphate/hydroxyapatite) alloplastic material. Method and Materials: Thirteen patients were selected. All patients were nonsmokers, systemically healthy, and diagnosed with chronic periodontitis; had not taken medications known to interfere with periodontal tissue health and healing; presented one Class II mandibular furcation defect with horizontal probing equal to or greater than 4 mm at buccal site. The clinical parameters evaluated were probing depth (PD), relative gingival margin position (RGMP), relative vertical clinical attachment level (RVCAL), and relative horizontal clinical attachment level (RHCAL). A paired Student t test was used to detect differences between the baseline and 6-month measurements, with the level of significance of .05. Results: After 6 months, the treatment produced a statistically significant reduction in PD and a significant gain in RVCAL and RHCAL, but no observable change in RGMP. RVCAL ranged from 13.77 (+/- 1.31) at baseline to 12.15 (+/- 1.29) after 6 months, with a mean change of -1.62 +/- 1.00 mm (P<.05). RHCAL ranged from 5.54 (+/- 0.75) to 2.92 (+/- 0.92), with a mean change of -2.62 +/- 0.63 mm (P<.05). After 6 months, 76.92% of the patients improved their diagnosis to Class I furcation defects while 23.08% remained as Class II. Conclusion: The present study has shown that positive clinical results may be expected from the combined treatment of Class II furcation defects with EMD and beta TCP/HA, especially considering the gain of horizontal attachment level. Despite this result, controlled clinical studies are needed to confirm our outcomes.en
dc.description.affiliationUniv Estadual Campinas, Piracicaba Dent Sch, Div Periodont, Dept Prosthodont &Periodont, Sao Paulo, Brazil
dc.description.affiliationState Univ Sao Paulo UNESP, Div Periodont, Coll Dent, Sao Paulo, Brazil
dc.description.affiliationUnespState Univ Sao Paulo UNESP, Div Periodont, Coll Dent, Sao Paulo, Brazil
dc.format.extent199-205
dc.identifierhttp://qi.quintessenz.de/index.php?doc=abstract&abstractID=32988
dc.identifier.citationQuintessence International. Hanover Park: Quintessence Publishing Co Inc, v. 46, n. 3, p. 199-205, 2015.
dc.identifier.doi10.3290/j.qi.a32988
dc.identifier.issn0033-6572
dc.identifier.lattes7008114923397947
dc.identifier.urihttp://hdl.handle.net/11449/129724
dc.identifier.wosWOS:000351715400003
dc.language.isoeng
dc.publisherQuintessence Publishing Co Inc
dc.relation.ispartofQuintessence International
dc.relation.ispartofjcr1.088
dc.relation.ispartofsjr0,563
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectClass II furcation defectsen
dc.subjectEnamel matrix protein derivativeen
dc.subjectPeriodontal regenerationen
dc.subjectSynthetic bone substituteen
dc.titleEnamel matrix protein derivative plus synthetic bone substitute for the treatment of mandibular Class II furcation defects: a case seriesen
dc.typeArtigo
dcterms.rightsHolderQuintessence Publishing Co Inc
unesp.author.lattes7008114923397947
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Ciência e Tecnologia, São José dos Campospt

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