Association between phase angle, anthropometric measurements, and lipid profile in HCV-infected patients

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dc.contributor.authorDorna, Mariana De Souza
dc.contributor.authorCosta, Nara Aline
dc.contributor.authorOliveira, Erick Prado De
dc.contributor.authorSassaki, Ligia Yukie [UNESP]
dc.contributor.authorRomeiro, Fernando Gomes [UNESP]
dc.contributor.authorPaiva, Sergio Alberto Rupp de [UNESP]
dc.contributor.authorMinicucci, Marcos Ferreira [UNESP]
dc.contributor.authorSilva, Giovanni Faria [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionFederal University of Uberlandia School of Medicine
dc.date.accessioned2014-09-30T18:18:33Z
dc.date.available2014-09-30T18:18:33Z
dc.date.issued2013-12-01
dc.description.abstractOBJECTIVE: The objective of this study was to investigate the associations between phase angle, anthropometric measurements, and lipid profile in patients chronically infected with the hepatitis C virus. METHODS: A total of 160 consecutive patients chronically infected with the hepatitis C virus and who received treatment at the hepatitis C outpatient unit of our hospital from April 2010 to May 2011 were prospectively evaluated. Bioelectrical impedance analysis, anthropometric measurements, and serum lipid profile analysis were performed. RESULTS: Twenty-five patients were excluded. A total of 135 patients with a mean age of 49.8±11.4 years were studied. Among these patients, 60% were male. The phase angle and BMI means were 6.5±0.8° and 26.5±4.8 kg/m2, respectively. Regarding anthropometric variables, mid-arm circumference, mid-arm muscle circumference, and arm muscle area had a positive correlation with phase angle. In contrast, when analyzing the lipid profile, only HDL was inversely correlated with phase angle. However, in multiple regression models adjusted for age and gender, only mid-arm circumference (p = 0.005), mid-arm muscle circumference (p = 0.003), and arm muscle circumference (p = 0.001) were associated with phase angle in hepatitis C virus-infected patients. CONCLUSIONS: In conclusion, phase angle is positively correlated with anthropometric measures in our study. However, there is no association between phase angle and lipid profile in these patients. Our results suggest that phase angle is related to lean body mass in patients chronically infected with hepatitis C virus.en
dc.description.affiliationUniversidade Estadual Paulista Julio de Mesquita Filho Department of Internal Medicine
dc.description.affiliationFederal University of Uberlandia School of Medicine
dc.description.affiliationUnespUniversidade Estadual Paulista Julio de Mesquita Filho Department of Internal Medicine
dc.format.extent1555-1558
dc.identifierhttp://dx.doi.org/10.6061/clinics/2013(12)13
dc.identifier.citationClinics. Faculdade de Medicina / USP, v. 68, n. 12, p. 1555-1558, 2013.
dc.identifier.doi10.6061/clinics/2013(12)13
dc.identifier.fileS1807-59322013001201555.pdf
dc.identifier.issn1807-5932
dc.identifier.lattes6322604200510676
dc.identifier.lattes4734747821898178
dc.identifier.lattes7438704034471673
dc.identifier.scieloS1807-59322013001201555
dc.identifier.urihttp://hdl.handle.net/11449/109667
dc.identifier.wosWOS:000329985900013
dc.language.isoeng
dc.publisherUniversidade de São Paulo (USP), Faculdade de Medicina
dc.relation.ispartofClinics
dc.relation.ispartofjcr1.245
dc.relation.ispartofsjr0,536
dc.rights.accessRightsAcesso aberto
dc.sourceSciELO
dc.subjectPhase Angleen
dc.subjectHepatitis Cen
dc.subjectCholesterolen
dc.subjectAnthropometryen
dc.subjectBioelectrical Impedance Analysisen
dc.titleAssociation between phase angle, anthropometric measurements, and lipid profile in HCV-infected patientsen
dc.typeArtigo
unesp.author.lattes6322604200510676
unesp.author.lattes4734747821898178
unesp.author.lattes7438704034471673
unesp.author.orcid0000-0002-5980-4367[7]
unesp.author.orcid0000-0003-4412-1990[6]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

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