Cell wall fractions from Paracoccidioides brasiliensis induce hypergammaglobulinemia

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dc.contributor.authorOliveira, Silvio Luis de [UNESP]
dc.contributor.authorSilva, Marcelo Fernandes da [UNESP]
dc.contributor.authorSoares, Angela Maria Victoriano de Campos [UNESP]
dc.contributor.authorSilva, Celio Lopes
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2014-05-27T11:17:30Z
dc.date.available2014-05-27T11:17:30Z
dc.date.issued1993-01-01
dc.description.abstractThe antibody response against the antigen sheep red blood cells (SRBC) was investigated in mice pre-treated with formalin-killed Paracoccidioides brasiliensis or with cell wall fractions of the fungus. Pre-treatment with P. brasiliensis, as well as with the F1 fraction and beta-glucan significantly increased the anti-SRBC antibody response in the experimental groups as compared to the control group that received only SRBC. This immunomodulatory effect varied with the different doses employed and with pre-treatment time. We conclude that the cell wall fractions of P. brasiliensis might play an important role in the hypergammaglobulinemia associated with Paracoccidioidomycosis. © 1993 Kluwer Academic Publishers.en
dc.description.affiliationDepartment of Microbiology and Immunology UNESP, Botucatu, SP
dc.description.affiliationDepartment of Parasitology, Microbiology and Immunology, School of Medicine of Ribeirao Preto University of Sao Paulo, Ribeirao Preto, SP, 14049 -900
dc.description.affiliationUnespDepartment of Microbiology and Immunology UNESP, Botucatu, SP
dc.format.extent1-5
dc.identifierhttp://dx.doi.org/10.1007/BF01103346
dc.identifier.citationMycopathologia, v. 121, n. 1, p. 1-5, 1993.
dc.identifier.doi10.1007/BF01103346
dc.identifier.issn0301-486X
dc.identifier.issn1573-0832
dc.identifier.lattes8418958338241095
dc.identifier.scopus2-s2.0-0027349345
dc.identifier.urihttp://hdl.handle.net/11449/64333
dc.language.isoeng
dc.relation.ispartofMycopathologia
dc.relation.ispartofjcr1.476
dc.relation.ispartofsjr0,597
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectBeta-glucan
dc.subjectCell wall
dc.subjectHypergammaglobulinemia
dc.subjectParacoccidioides brasiliensis
dc.subjectParacoccidioidomycosis
dc.titleCell wall fractions from Paracoccidioides brasiliensis induce hypergammaglobulinemiaen
dc.typeArtigo
dcterms.licensehttp://www.springer.com/open+access/authors+rights
unesp.author.lattes8418958338241095
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatupt

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Artigos - Microbiologia e Imunologia - IBB