Geographic and Educational Factors and Risk of the First Peritonitis Episode in Brazilian Peritoneal Dialysis Study (BRAZPD) Patients

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dc.contributor.authorMartin, Luis Cuadrado [UNESP]
dc.contributor.authorCaramori, Jacqueline Socorro Costa Teixeira [UNESP]
dc.contributor.authorFernandes, Natalia
dc.contributor.authorDivino-Filho, Jose C.
dc.contributor.authorPecoits-Filho, Roberto
dc.contributor.authorBarretti, Pasqual [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal de Juiz de Fora (UFJF)
dc.contributor.institutionKarolinska Inst
dc.contributor.institutionPontifícia Universidade Católica do Paraná (PUCPR)
dc.date.accessioned2014-05-20T13:33:24Z
dc.date.available2014-05-20T13:33:24Z
dc.date.issued2011-08-01
dc.description.abstractBackground and objectives Peritonitis remains as the most frequent cause of peritoneal dialysis (PD) failure, impairing patient's outcome. No large multicenter study has addressed socioeconomic, educational, and geographic issues as peritonitis risk factors in countries with a large geographic area and diverse socioeconomic conditions, such as Brazil.Design, setting, participants, & measurements Incident PD patients recruited from 114 dialysis centers and reporting to BRAZPD, a multicenter observational study, from December 2004 through October 2007 were included. Clinical, dialysis-related, demographic, and socioeconomic variables were analyzed. Patients were followed up until their first peritonitis. Cox proportional model was used to determine independent factors associated with peritonitis.Results In a cumulative follow-up of 2032 patients during 22.026 patient-months, 474 (23.3%) presented a first peritonitis episode. In contrast to earlier findings, PD modality, previous hemodialysis, diabetes, gender, age, and family income were not risk predictors. Factors independently associated with increased hazard risk were lower educational level, non-white race, region where patients live, shorter distance from dialysis center, and lower number of patients per center.Conclusions Educational level and geographic factors as well as race and center size are associated with risk for the first peritonitis, independent of socioeconomic status, PD modality, and comorbidities. Clin J Am Soc Nephrol 6: 1944-1951, 2011. doi: 10.2215/CJN.11431210en
dc.description.affiliationUNESP, Botucatu Med Sch, Dept Internal Med, BR-18618000 Botucatu, SP, Brazil
dc.description.affiliationUniv Fed Juiz de Fora, Dept Nephrol, Juiz de Fora, MG, Brazil
dc.description.affiliationKarolinska Inst, CLINTEC, Div Baxter Novum & Renal Med, Stockholm, Sweden
dc.description.affiliationPontificia Univ Catolica Parana, Curitiba, Parana, Brazil
dc.description.affiliationUnespUNESP, Botucatu Med Sch, Dept Internal Med, BR-18618000 Botucatu, SP, Brazil
dc.description.sponsorshipBaxter Healthcare, Brazil
dc.format.extent1944-1951
dc.identifierhttp://dx.doi.org/10.2215/CJN.11431210
dc.identifier.citationClinical Journal of The American Society of Nephrology. Washington: Amer Soc Nephrology, v. 6, n. 8, p. 1944-1951, 2011.
dc.identifier.doi10.2215/CJN.11431210
dc.identifier.issn1555-9041
dc.identifier.lattes5496411983893479
dc.identifier.lattes4923203168446615
dc.identifier.orcid0000-0003-4979-4836
dc.identifier.urihttp://hdl.handle.net/11449/11444
dc.identifier.wosWOS:000293721400022
dc.language.isoeng
dc.publisherAmer Soc Nephrology
dc.relation.ispartofClinical Journal of The American Society of Nephrology
dc.relation.ispartofjcr5.835
dc.relation.ispartofsjr3,099
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.titleGeographic and Educational Factors and Risk of the First Peritonitis Episode in Brazilian Peritoneal Dialysis Study (BRAZPD) Patientsen
dc.typeArtigo
dcterms.licensehttp://cjasn.asnjournals.org/site/misc/about.xhtml
dcterms.rightsHolderAmer Soc Nephrology
unesp.author.lattes5496411983893479[6]
unesp.author.lattes4923203168446615
unesp.author.orcid0000-0002-0255-6710[5]
unesp.author.orcid0000-0003-4979-4836[6]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

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