Apert syndrome: Factors involved in the cognitive development

Página do item simplificado
dc.contributor.authorYacubian-Fernandes, Adriano [UNESP]
dc.contributor.authorPalhares Neto, Aristides Augusto [UNESP]
dc.contributor.authorGiglio, Alcir
dc.contributor.authorGabarra, Roberto Colichio [UNESP]
dc.contributor.authorZanini, Silvio
dc.contributor.authorPortela, Luis
dc.contributor.authorSilva, Mateus Violin
dc.contributor.authorPerosa, Gimol Benzaquen [UNESP]
dc.contributor.authorAbramides, Dagma
dc.contributor.authorPlese, José Píndaro P.
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionHospital Alemão Oswaldo Cruz
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:21:42Z
dc.date.available2014-05-27T11:21:42Z
dc.date.issued2005-12-01
dc.description.abstractApert syndrome is characterized by craniosynostosis, symmetric syndactyly and other systemic malformations, with mental retardation usually present. The objective of this study was to correlate brain malformations and timing for surgery with neuropsychological evaluation. We also tried to determine other relevant aspects involved in cognitive development of these patients such as social classification of families and parents' education. Eighteen patients with Apert syndrome were studied, whose ages were between 14 and 322 months. Brain abnormalities were observed in 55.6% of them. The intelligence quotient or developmental quotient values observed were between 45 and 108. Mental development was related to the quality of family environment and parents' education. Mental development was not correlated to brain malformation or age at time of operation. In conclusion, quality of family environment was the most significant factor directly involved in mental development of patients with Apert syndrome.en
dc.description.affiliationDepartment of Craniofacial Surgery Hospital de Reabilitação de Anomalias Craniofaciais University of Sao Paulo (USP), Bauru, SP
dc.description.affiliationDepartment of Neuroradiology Hospital Alemão Oswaldo Cruz, São Paulo SP
dc.description.affiliationDepartment of Neurosurgery Hospital Das Clínicas University of Sao Paulo (USP), São Paulo SP
dc.description.affiliationDepartment of Neurology and Psychiatry Hospital Das Clínicas University of the State of São Paulo (UNESP), Botucatu SP
dc.description.affiliationDepartment of Surgery Hospital Das Clínicas University of the State of Sao Paulo (UNESP), Botucatu SP
dc.description.affiliationDepartment of Fonoaudiology Faculty of Odontology University of Sao Paulo (USP), Bauru SP
dc.description.affiliation, Rua Moyses Leme da Silva 1-30, 17017-335 Bauru SP
dc.description.affiliationUnespDepartment of Neurology and Psychiatry Hospital Das Clínicas University of the State of São Paulo (UNESP), Botucatu SP
dc.description.affiliationUnespDepartment of Surgery Hospital Das Clínicas University of the State of Sao Paulo (UNESP), Botucatu SP
dc.format.extent963-968
dc.identifierhttp://dx.doi.org/10.1590/S0004-282X2005000600011
dc.identifier.citationArquivos de Neuro-Psiquiatria, v. 63, n. 4, p. 963-968, 2005.
dc.identifier.doi10.1590/S0004-282X2005000600011
dc.identifier.file2-s2.0-32244442191.pdf
dc.identifier.issn0004-282X
dc.identifier.lattes6664825590096912
dc.identifier.lattes7643097631069139
dc.identifier.scieloS0004-282X2005000600011
dc.identifier.scopus2-s2.0-32244442191
dc.identifier.urihttp://hdl.handle.net/11449/68562
dc.identifier.wosWOS:000233987900011
dc.language.isoeng
dc.relation.ispartofArquivos de Neuro-Psiquiatria
dc.relation.ispartofjcr1.015
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectApert syndrome
dc.subjectMagnetic resonance
dc.subjectMental development
dc.subjectacrocephalosyndactyly
dc.subjectadolescent
dc.subjectadult
dc.subjectbrain malformation
dc.subjectchild
dc.subjectclassification
dc.subjectclinical article
dc.subjectcognitive development
dc.subjectcontrolled study
dc.subjectcorrelation analysis
dc.subjecteducation
dc.subjectfamily
dc.subjectfamily attitude
dc.subjectfemale
dc.subjecthuman
dc.subjectintelligence quotient
dc.subjectmale
dc.subjectmental development
dc.subjectneuropsychological test
dc.subjectparent
dc.subjectparental attitude
dc.subjectqualitative analysis
dc.subjectsocial aspect
dc.subjectAcrocephalosyndactylia
dc.subjectAdolescent
dc.subjectAdult
dc.subjectChild
dc.subjectChild, Preschool
dc.subjectCognition Disorders
dc.subjectEducational Status
dc.subjectFemale
dc.subjectHumans
dc.subjectInfant
dc.subjectIntelligence
dc.subjectMagnetic Resonance Imaging
dc.subjectMale
dc.subjectNeuropsychological Tests
dc.subjectPregnancy
dc.subjectSocioeconomic Factors
dc.titleApert syndrome: Factors involved in the cognitive developmenten
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/anp/paboutj.htm
unesp.author.lattes6664825590096912
unesp.author.lattes7643097631069139
unesp.author.lattes8588587034751584[2]
unesp.author.orcid0000-0002-3484-862X[2]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

Arquivos

Pacote Original
Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
2-s2.0-32244442191.pdf
Tamanho:
210.12 KB
Formato:
Adobe Portable Document Format
Baixar

Coleções

Artigos - Neurologia, Psicologia e Psiquiatria - FMB
Artigos - Hospital das Clínicas (HC) - Botucatu