Gene discovery in Boophilus microplus, the cattle tick - the transcriptomes of ovaries, salivary glands, and hemocytes

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dc.contributor.authorSantos, IKFD
dc.contributor.authorValenzuela, J. G.
dc.contributor.authorRibeiro, JMC
dc.contributor.authorDe Castro, M.
dc.contributor.authorCosta, J. N.
dc.contributor.authorCosta, A. M.
dc.contributor.authorDa Silva, E. R.
dc.contributor.authorNeto, OBR
dc.contributor.authorRocha, C.
dc.contributor.authorDaffre, S.
dc.contributor.authorFerreira, B. R.
dc.contributor.authorDa Silva, J. S.
dc.contributor.authorSzabo, M. P.
dc.contributor.institutionEmpresa Brasileira de Pesquisa Agropecuária (EMBRAPA)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionNIAID
dc.date.accessioned2014-05-20T15:26:20Z
dc.date.available2014-05-20T15:26:20Z
dc.date.issued2004-01-01
dc.description.abstractThe quest for new control strategies for ticks can profit from high throughput genomics. In order to identify genes that are involved in oogenesis and development, in defense, and in hematophagy, the transcriptomes of ovaries, hemocytes, and salivary glands from rapidly ingurgitating females, and of salivary glands from males of Boophilus microplus were PCR amplified, and the expressed sequence tags (EST) of random clones were mass sequenced. So far, more than 1,344 EST have been generated for these tissues, with approximately 30% novelty, depending on the the tissue studied. To date approximately 760 nucleotide sequences from B. microplus are deposited in the NCBI database. Mass sequencing of partial cDNAs of parasite genes can build up this scant database and rapidly generate a large quantity of useful information about potential targets for immunobiological or chemical control.en
dc.description.affiliationEmpresa Brasileira Pesquisa Agropecuaria, Ctr Genet Resources & Biotechnol, Brasilia, DF, Brazil
dc.description.affiliationUniv São Paulo, Ribeirao Preto Sch Med, BR-14049 Ribeirao Preto, SP, Brazil
dc.description.affiliationUniv Estadual Paulista, Sch Agron & Vet Sci, Jaboticabal, SP, Brazil
dc.description.affiliationNIAID, Sect Vector Biol, NIH, Bethesda, MD 20892 USA
dc.description.affiliationUniv São Paulo, Inst Biol, São Paulo, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Sch Agron & Vet Sci, Jaboticabal, SP, Brazil
dc.format.extent242-246
dc.identifierhttp://dx.doi.org/10.1196/annals.1307.037
dc.identifier.citationImpact of Ecological Changes on Tropical Animal Health and Disease Control. New York: New York Acad Sciences, v. 1026, p. 242-246, 2004.
dc.identifier.doi10.1196/annals.1307.037
dc.identifier.issn0077-8923
dc.identifier.urihttp://hdl.handle.net/11449/36511
dc.identifier.wosWOS:000226725500037
dc.language.isoeng
dc.publisherNew York Acad Sciences
dc.relation.ispartofImpact of Ecological Changes on Tropical Animal Health and Disease Control
dc.relation.ispartofjcr4.277
dc.relation.ispartofsjr2,108
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectBoophilus micropluspt
dc.subjecttranscriptomespt
dc.subjectsalivary glandspt
dc.subjectovarypt
dc.subjecthemocytespt
dc.titleGene discovery in Boophilus microplus, the cattle tick - the transcriptomes of ovaries, salivary glands, and hemocytesen
dc.typeArtigo
dcterms.licensehttp://www.nyas.org/Footer/TermsofUse.aspx
dcterms.rightsHolderNew York Acad Sciences
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Agrárias e Veterinárias, Jaboticabalpt

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Artigos - Patologia Veterinária - FCAV