Oral lichen planus versus oral lichenoid reaction: Difficulties in the diagnosis

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dc.contributor.authorPrado, Renata Falchete do
dc.contributor.authorMarocchio, Luciana Sassa
dc.contributor.authorFelipini, Renata Callestini [UNESP]
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:23:56Z
dc.date.available2014-05-27T11:23:56Z
dc.date.issued2009-07-01
dc.description.abstractLichen planus (LP) is a mucocutaneous disease with well-established clinical and microscopic features. The oral mucosa and skin may present clinical and microscopic alterations similar to those observed in LP, called lichenoid reactions (LRs), which are triggered by systemic or topical etiological agents. The difficulties faced to establish the differential diagnosis between the two pathologies were investigated in the literature. It was observed that the etiology of LP is still under discussion, with a tendency to self-immunity, while the etiology of LRs is related to the contact with specific agents, such as metallic restorative materials, resins, and drugs, allowing the establishment of a cause-effect relationship. In this case, the disease is caused by the antigen fixation in the epithelial cells, which are destructed by the immune system. Based on these data, protocols are suggested for this differentiation. The important role played by the integration between the clinician and the oral pathologist in the diagnostic process is highlighted. The treatment of LP comprises mainly the utilization of corticosteroids and the LR is treated by removal of the causal factor. Differentiation between the two diseases allows an effective and correct therapeutic approach.en
dc.description.affiliationDepartment of Biosciences and Oral Diagnosis São José Dos Campos Dental School São José Dos Campos
dc.description.affiliationDepartment of Oral Pathology Dental School University of São Paulo (USP-FO), São Paulo
dc.description.affiliationDepartment of Pathology and Clinical Propedeutics Araçatuba Dental School São Paulo State University (UNESP), Araçatuba, São Paulo
dc.description.affiliationUnespDepartment of Pathology and Clinical Propedeutics Araçatuba Dental School São Paulo State University (UNESP), Araçatuba, São Paulo
dc.format.extent361-364
dc.identifierhttp://dx.doi.org/10.4103/0970-9290.57375
dc.identifier.citationIndian Journal of Dental Research, v. 20, n. 3, p. 361-364, 2009.
dc.identifier.doi10.4103/0970-9290.57375
dc.identifier.issn0970-9290
dc.identifier.issn1998-359X
dc.identifier.lattes6207099947394016
dc.identifier.scopus2-s2.0-70449572267
dc.identifier.urihttp://hdl.handle.net/11449/71073
dc.language.isoeng
dc.relation.ispartofIndian Journal of Dental Research
dc.relation.ispartofsjr0,266
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectDiagnosis
dc.subjectLichen planus
dc.subjectLichenoid reactions
dc.subjectLiterature review
dc.subjectTherapy
dc.subjectautoimmune disease
dc.subjectcontact dermatitis
dc.subjectdifferential diagnosis
dc.subjecthuman
dc.subjectlichen planus
dc.subjectlichenoid eruption
dc.subjectmouth disease
dc.subjectpathology
dc.subjectreview
dc.subjectAutoimmune Diseases
dc.subjectDermatitis, Contact
dc.subjectDiagnosis, Differential
dc.subjectHumans
dc.subjectLichen Planus, Oral
dc.subjectLichenoid Eruptions
dc.subjectMouth Diseases
dc.titleOral lichen planus versus oral lichenoid reaction: Difficulties in the diagnosisen
dc.typeArtigo
dcterms.licensehttp://www.jpgmonline.com/contributors.asp
unesp.author.lattes6207099947394016[3]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araçatubapt

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Artigos - Patologia e Propedêutica Clínica - FOA