Antidiarrheal activity of Guazuma ulmifolia Lam. (Sterculiaceae)

Página do item simplificado
dc.contributor.authorMichelin, Daniele C. [UNESP]
dc.contributor.authorde Almeida, Glalber C.
dc.contributor.authorGalina, Karen J. [UNESP]
dc.contributor.authorLopes, Gisely C.
dc.contributor.authorNakamura, Celso V.
dc.contributor.authorDias Filho, Benedito P.
dc.contributor.authorUeda-Nakamura, Tania
dc.contributor.authorSalgado, Hérida Regina Nunes [UNESP]
dc.contributor.authorPalazzo de Mello, Joao C.
dc.contributor.institutionUniversidade Estadual de Maringá (UEM)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T13:25:00Z
dc.date.available2014-05-20T13:25:00Z
dc.date.issued2010-09-01
dc.description.abstractThe high incidence of diarrhea in the population demands a search for new therapeutic options and easy access, mainly from plant-based sources. Leaves and bark of Guazuma ulmifolia Lam. (Sterculiaceae) are popularly employed against diarrhea. However, no information was found in the literature about this supposed property of the drug. In this study we evaluated in vivo antidiarrheal activity of stem bark extracts from G. ulmifolia in mice, and in vitro antimicrobial activity against Staphylococcus aureus, Escherichia coli, Bacillus subtilis, Salmonella sp., Shigella flexneri, and Pseudomonas aeruginosa by using the microdilution method. The n-BuOH semipurified fraction (GU#3) significantly reduced intestinal motility. The extracts did not show antimicrobial activity. G. ulmifolia Lam, had non-specific antidiarrheal, and antimotility activity in the experimental models studied, and could be used as an alternative treatment for non-infectious diarrhea.en
dc.description.affiliationUniversidade Estadual de Maringá (UEM), Programa Posgraduacao Ciencias Farmaceut, BR-87020900 Maringa, Parana, Brazil
dc.description.affiliationUniv Estadual Paulista, Programa Posgraduacao Farmacos & Med, BR-14801902 São Paulo, Brazil
dc.description.affiliationUniversidade Estadual de Maringá (UEM), Acad Farm, BR-87020900 Maringa, PR, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Programa Posgraduacao Farmacos & Med, BR-14801902 São Paulo, Brazil
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipFinanciadora de Estudos e Projetos (FINEP)
dc.description.sponsorshipFundação Araucária de Apoio ao Desenvolvimento Científico e Tecnológico do Paraná (FAADCT/PR)
dc.description.sponsorshipCOMCAP-UEM
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipINCT_if
dc.description.sponsorshipIdPADC-UNESP2003/7-I-
dc.format.extent1024-1028
dc.identifierhttp://www.latamjpharm.org/resumenes/29/6/LAJOP_29_6_2_6.pdf
dc.identifier.citationLatin American Journal of Pharmacy. La Plata: Colegio Farmaceuticos Provincia de Buenos Aires, v. 29, n. 6, p. 1024-1028, 2010.
dc.identifier.issn0326-2383
dc.identifier.urihttp://hdl.handle.net/11449/7900
dc.identifier.wosWOS:000283811100026
dc.language.isoeng
dc.publisherColegio Farmaceuticos Provincia de Buenos Aires
dc.relation.ispartofLatin American Journal of Pharmacy
dc.relation.ispartofjcr0.401
dc.relation.ispartofsjr0,152
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectAntidiarrheal activityen
dc.subjectAntimicrobial screeningen
dc.subjectCondensed tanninsen
dc.subjectGuazuma ulmifoliaen
dc.subjectSterculiaceaeen
dc.titleAntidiarrheal activity of Guazuma ulmifolia Lam. (Sterculiaceae)en
dc.typeArtigo
dcterms.rightsHolderColegio Farmaceuticos Provincia de Buenos Aires
unesp.author.orcid0000-0002-7532-3395[9]
unesp.author.orcid0000-0001-5057-3518[7]
unesp.author.orcid0000-0002-0385-340X[8]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Farmacêuticas, Araraquarapt

Arquivos

Licença do Pacote
Agora exibindo 1 - 2 de 2
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:

Coleções

Artigos - Fármacos e Medicamentos - FCFAR