A simple and rapid screening method for sulfonamides in honey using a flow injection system coupled to a liquid waveguide capillary cell
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Data
2014-04-01
Autores
Catelani, Tiago Augusto [UNESP]
Toth, Ildiko Vargane
Lima, Jose L. F. C.
Pezza, Leonardo [UNESP]
Pezza, Helena Redigolo [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Elsevier B.V.
Resumo
A rapid and simple screening method was developed for the determination of sulfonamides in honey samples by flow injection analysis (FIA) coupled to a liquid waveguide capillary cell. The proposed method is based on the reaction between sulfonamides and p-dimethylaminocinnamaldehyde (p-DAC) in the presence of sodium dodecylsulate (SDS) in dilute acid medium (hydrochloric acid), with the reaction product being measured spectrophotometrically at lambda(max)=565 nm. Experimental design methodology was used to optimize the analytical conditions. The proposed technique was applied to the determination of sulfonamides (sulfaquinoxaline, sulfadimethoxine, and sulfathiazole) in honey samples, in a concentration range from 6.00 x 10(-3) to 1.15 x 10(-1) mg L-1. The detection (LOD) and quantification (LOQ) limits were 1.66 x 10(-3) and 5.54 x 10(-3) mg L-1, respectively. Positive and false positive samples were also analyzed by a confirmatory HPLC method. The proposed system enables the screening of sulfonamides in honey samples with a low number of false positive results, with fast response therefore offers a new tool for consumer protection. (C) 2013 Elsevier B.V. All rights reserved.
Descrição
Palavras-chave
Flow injection analysis (FIA), Screening, Sulfonamides, Liquid waveguide capillary cell (LWCC), Green chemistry
Como citar
Talanta. Amsterdam: Elsevier Science Bv, v. 121, p. 281-287, 2014.