LOSS OF THE SEX-CHROMOSOME IN HUMAN NEOPLASIAS OF THE NERVOUS-SYSTEM
Carregando...
Arquivos
Data
1994-06-01
Autores
Rogatto, Silvia Regina [UNESP]
Rainho, C. A.
Neto, J. B.
Casartelli, C.
Título da Revista
ISSN da Revista
Título de Volume
Editor
Soc Brasil Genetica
Resumo
Thirty-eight tumors (five grade I-II astrocytomas, three grade III astrocytomas, four glioblastomas, one oligodendroglioma, four ependymomas, one pineocytoma, three medulloblastomas, four acoustic nerve neurinomas, one intraspinal neurinoma, one neurofibroma, 10 meningiomas, and one craniopharyngioma) and three benign lesions of the nervous system were evaluated cytogenetically after in vitro culture. Sex chromosome loss was detected in 56% of the cases (-X in 13 of the 25 female patients and -Y in nine of the 16 male patients). The objective of the present report was to study the role of this abnormality in cells of the nervous system.
Descrição
Palavras-chave
Como citar
Revista Brasileira de Genetica. Ribeirao Pret: Soc Brasil Genetica, v. 17, n. 2, p. 215-222, 1994.