Antibiotic 26-deoxylaidlomycin isolated from Streptomyces sp. Ar386 from Brazilian soil

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Data

1996-12-01

Autores

Ujikawa, Keidi [UNESP]
Vilegas, Wagner [UNESP]
Vilegas, Janete H. Y.
Llabrés, Gabriel

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Resumo

An actinomycete strain (Ar386) was isolated from the soil of the Araraquara regio, SP, Brazil. The strain, named Streptomyces jacareensis, formed irregular rayed, rugose, grayish-white mycelium with sinuous, branched hyphae carrying rare isolated spores; assimilated glucose, galactose, inositol, ribose, maltose, sucrose, melibiose and starch but not mannitol, rhamnose, arabinose, xylose, lactose and raffinose; and contained LL- diaminopimelic acid in its cell wall. An antibiotic active against Gram- positive bacteria, which was characterized as being 26-deoxylaidlomycin and which may have application against poultry coccidiosis, was isolated from cultures of the strain. This was the first isolation of this antibiotic from a microorganism of the genus Streptomyces and also the first isolation of this antibiotic in Brazil.

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Palavras-chave

26-Deoxylaidlomycin, Coccidiostatic, Polyether antibiotic, Streptomyces jacareensis, Streptomyces sp. Ar386, 26 deoxylaidlomycin, antibiotic agent, arabinose, diaminopimelic acid, galactose, glucose, inositol, lactose, maltose, mannitol, melibiose, raffinose, rhamnose, ribose, starch, sucrose, xylose, antibiotic biosynthesis, antimicrobial activity, bacterial metabolism, bacterium isolation, Brazil, coccidiosis, controlled study, nonhuman, poultry, soil microflora, Streptomyces, streptomyces jacareensis, Monensin, Soil Microbiology

Como citar

Revista Latinoamericana de Microbiologia, v. 38, n. 3-4, p. 185-191, 1996.