Approach to prophylactic measures for central venous catheter-related infections in hemodialysis: A critical review

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dc.contributor.authorSilva, Tricya N. V. [UNESP]
dc.contributor.authorMarchi, Daniel de [UNESP]
dc.contributor.authorMendes, Marcela L. [UNESP]
dc.contributor.authorBarretti, Pasqual [UNESP]
dc.contributor.authorPonce, Daniela [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-12-03T13:07:01Z
dc.date.available2014-12-03T13:07:01Z
dc.date.issued2014-01-01
dc.description.abstractVascular access is the major risk factor for bacteremia, hospitalization, and mortality among hemodialysis (HD) patients. The type of vascular access most associated with bloodstream infection is central venous catheter (CVC). The incidence of catheter-related bacteremia ranges between 0.6 and 6.5 episodes per 1000 catheter days and increases linearly with the duration of catheter use. Given the high prevalence of CVC use and its direct association with catheter-related bacteremia, which adversely impacts morbidity and mortality rates and costs among HD patients, several prevention measures aimed at reducing the rates of CVC-related infections have been proposed and implemented. As a result, a large number of clinical trials, systematic reviews, and meta-analyses have been conducted in order to assess the effectiveness, clinical applicability, and long-term adverse effects of such measures. In the following article, prophylactic measures against CVC-related infections in HD patients and their possible advantages and limitations will be discussed, and the more recent literature on clinical experience with prophylactic antimicrobial lock therapy in HD CVCs will be reviewed.en
dc.description.affiliationUniv Sao Paulo State UNESP, Botucatu Sch Med, Botucatu, SP, Brazil
dc.description.affiliationUnespUniv Sao Paulo State UNESP, Botucatu Sch Med, Botucatu, SP, Brazil
dc.format.extent15-23
dc.identifierhttp://dx.doi.org/10.1111/hdi.12071
dc.identifier.citationHemodialysis International. Hoboken: Wiley-blackwell, v. 18, n. 1, p. 15-23, 2014.
dc.identifier.doi10.1111/hdi.12071
dc.identifier.issn1492-7535
dc.identifier.lattes5496411983893479
dc.identifier.orcid0000-0003-4979-4836
dc.identifier.urihttp://hdl.handle.net/11449/111169
dc.identifier.wosWOS:000334518900004
dc.language.isoeng
dc.publisherWiley-Blackwell
dc.relation.ispartofHemodialysis International
dc.relation.ispartofjcr1.237
dc.relation.ispartofsjr0,554
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjecttunneled central catheteren
dc.subjectcatheter-related bacteremiaen
dc.subjectantibiotic lock therapyen
dc.subjectHemodialysisen
dc.titleApproach to prophylactic measures for central venous catheter-related infections in hemodialysis: A critical reviewen
dc.typeArtigo
dcterms.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dcterms.rightsHolderWiley-Blackwell
unesp.author.lattes5496411983893479[4]
unesp.author.orcid0000-0003-4979-4836[4]
unesp.author.orcid0000-0002-6178-6938[5]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

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