Alterações eletromiográficas e histopatológicas da musculatura de cães naturalmente infectados por Leishmania infantum

Página do item simplificado
dc.contributor.authorFerraro, Gisela Cristiane [UNESP]
dc.contributor.authorMachado, Gisele Fabrino [UNESP]
dc.contributor.authorLaurenti, Márcia Dalastra
dc.contributor.authorBueno de Camargo, Mauro Henrique [UNESP]
dc.contributor.authorGomes, Ana Amélia Domingues [UNESP]
dc.contributor.authorCosta, Denis Carvalho [UNESP]
dc.contributor.authorVieira, Camila Mariana [UNESP]
dc.contributor.authorSimões, Celina Bertelli [UNESP]
dc.contributor.authorLima, Valéria Marçal Felix de [UNESP]
dc.contributor.authorMarcondes, Mary [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Federal do Vale do São Francisco (UNIVASF)
dc.date.accessioned2014-05-27T11:27:24Z
dc.date.available2014-05-27T11:27:24Z
dc.date.issued2012-12-01
dc.description.abstractThe aim of this study was to evaluate the electromyographic and histopathological changes in skeletal muscles of dogs naturally infected by L. infantum. Twenty five mixed breed adult dogs with parasitological, molecular and serological diagnosis were selected. The evaluated muscles were: triceps brachial, extensor carpi radialis, biceps femoris and gastrocnemius. One dog had locomotor clinical signs with hind limbs paresis associated with severe muscle atrophy. Twenty-three (92%) had some type of muscular change, and in 22 (88%) such changes were directly identified by electromyography. Even without any clinical signs of the disease, 10 (40%) dogs had electromyographic and histopathological changes. Leishmania antigens were detected in muscles of four (16%) dogs. The electromyographic evaluation indicated the occurrence of chronic polymyositis in 13 (52%) dogs, the presence of both acute and chronic muscle inflammation four (16%), acute myopathy in two (8%) and absence of electromyographic abnormalities in three (12%) dogs. The most frequently observed histopathological changes were degeneration and necrosis of myofibers and inflammatory infiltration observed in 12 (48%) dogs. Other changes were decreased diameter of muscle fibers in 15 (60%) and peri or endomysial fibrosis in 14 (56%) animals. The changes observed in the present study showed that even in the absence of clinical signs, most dogs infected by Leishmania infantum have chronic polymyositis.en
dc.description.affiliationFaculdade de Ciências Agrárias e Veterinárias Universidade Estadual Paulista, Jaboticabal - SP
dc.description.affiliationFaculdade de Medicina Veterinária Universidade Estadual Paulista, Araçatuba - SP
dc.description.affiliationFaculdade de Medicina Universidade de São Paulo, São Paulo - SP
dc.description.affiliationFaculdade de Medicina Veterinária Universidade Federal do Vale do São Francisco, Petrolina - PE
dc.description.affiliationUnespFaculdade de Ciências Agrárias e Veterinárias Universidade Estadual Paulista, Jaboticabal - SP
dc.description.affiliationUnespFaculdade de Medicina Veterinária Universidade Estadual Paulista, Araçatuba - SP
dc.format.extent404-413
dc.identifierhttp://www.revistas.usp.br/bjvras/article/view/51735
dc.identifier.citationBrazilian Journal of Veterinary Research and Animal Science, v. 49, n. 5, p. 404-413, 2012.
dc.identifier.file2-s2.0-84874508436.pdf
dc.identifier.issn1413-9596
dc.identifier.issn1678-4456
dc.identifier.lattes0310405558125634
dc.identifier.lattes4875352337860036
dc.identifier.lattes1817946671090010
dc.identifier.scopus2-s2.0-84874508436
dc.identifier.urihttp://hdl.handle.net/11449/74023
dc.language.isoeng
dc.language.isopor
dc.relation.ispartofBrazilian Journal of Veterinary Research and Animal Science
dc.relation.ispartofsjr0,225
dc.relation.ispartofsjr0,225
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectCanine visceral leishmaniasis
dc.subjectLeishmania infantum
dc.subjectMyopathy
dc.subjectPolymyositis
dc.titleAlterações eletromiográficas e histopatológicas da musculatura de cães naturalmente infectados por Leishmania infantumpt
dc.title.alternativeMuscular electromyographic and histopathologic changes in dogs naturally infected by Leishmania infantumen
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/bjvras/paboutj.htm
unesp.author.lattes0310405558125634
unesp.author.lattes4875352337860036
unesp.author.lattes1817946671090010
unesp.author.orcid0000-0001-6931-4479[10]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina Veterinária, Araçatubapt

Arquivos

Pacote Original
Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
2-s2.0-84874508436.pdf
Tamanho:
770.14 KB
Formato:
Adobe Portable Document Format
Baixar

Coleções

Artigos - Clínica, Cirurgia e Reprodução Animal - FMVA