Mechanism of action of Bioactive Endodontic Materials

Página do item simplificado
dc.contributor.authorEstrela, Carlos
dc.contributor.authorCintra, Luciano Tavares Angelo [UNESP]
dc.contributor.authorDuarte, Marco Antônio Hungaro
dc.contributor.authorRossi-Fedele, Giampiero
dc.contributor.authorGavini, Giulio
dc.contributor.authorSousa-Neto, Manoel Damião
dc.contributor.institutionUniversidade Federal de Goiás (UFG)
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversity of Adelaide
dc.date.accessioned2023-07-29T16:07:58Z
dc.date.available2023-07-29T16:07:58Z
dc.date.issued2023-01-01
dc.description.abstractA continuous search for bioactive materials capable of supporting the replacement of damaged pulp tissue, with effective sealing potential and biocompatibility, has represented the attention of studies over the last decades. This study involves a narrative review of the literature developed by searching representative research in PUBMED/MEDLINE and searches in textbooks associated with the mechanism of action of bioactive materials (calcium hydroxide, mineral trioxide aggregate (MTA), and calcium silicate cements). The reflective analysis of the particularities of the chemical elements of these materials, considering the tissue and antibacterial mechanism of action, allows a better understanding of the characteristics and similarities in their tissue responses. Calcium hydroxide paste remains the antibacterial substance of choice as intracanal dressing for the treatment of root canal system infections. Calcium silicate cements, including MTA, show a favorable biological response with the stimulation of mineralized tissue deposition in sealed areas when in contact with connective tissue. This is due to the similarity between the chemical elements, especially ionic dissociation, the potential stimulation of enzymes in tissues, and the contribution towards an alkaline environment due to the pH of these materials. The behavior of bioactive materials, especially MTA and the new calcium silicate cements in the biological sealing activity, has been shown to be effective. Contemporary endodontics has access to bioactive materials with similar properties, which can stimulate a biological seal in lateral and furcation root perforations, root-end fillings and root fillings, pulp capping, pulpotomy, apexification, and regenerative endodontic procedures, in addition to other clinical conditions.en
dc.description.affiliationSchool of Dentistry Federal University of Goiás GO
dc.description.affiliationSchool of Dentistry São Paulo State University (Unesp)
dc.description.affiliationSchool of Dentistry University of São Paulo
dc.description.affiliationAdelaide Dental School University of Adelaide
dc.description.affiliationUnespSchool of Dentistry São Paulo State University (Unesp)
dc.format.extent1-11
dc.identifierhttp://dx.doi.org/10.1590/0103-6440202305278
dc.identifier.citationBrazilian dental journal, v. 34, n. 1, p. 1-11, 2023.
dc.identifier.doi10.1590/0103-6440202305278
dc.identifier.issn1806-4760
dc.identifier.scopus2-s2.0-85149638979
dc.identifier.urihttp://hdl.handle.net/11449/249741
dc.language.isoeng
dc.relation.ispartofBrazilian dental journal
dc.sourceScopus
dc.titleMechanism of action of Bioactive Endodontic Materialsen
dc.typeResenha
unesp.author.orcid0000-0002-1488-0366[1]
unesp.author.orcid0000-0003-2348-7846[2]
unesp.author.orcid0000-0003-3051-737X[3]
unesp.author.orcid0000-0002-8287-1226[4]
unesp.author.orcid0000-0002-3254-2504[5]
unesp.author.orcid0000-0002-7696-7600[6]

Arquivos

Coleções

Artigos - Odontologia Restauradora - FOA