The Lanz® endotracheal tube decreases tracheal injury in dogs

Página do item simplificado
dc.contributor.authorAbud, Tania Mara Vilela
dc.contributor.authorBraz, José Reinaldo Cerqueira
dc.contributor.authorMartins, Regina Helena Garcia
dc.contributor.authorGregório, Elisa Aparecida [UNESP]
dc.contributor.authorSaldanha, João Carlos
dc.contributor.authorRaiza, Ana Carolina Pasquini
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Federal do Triângulo Mineiro (UFTM)
dc.date.accessioned2014-05-20T13:51:27Z
dc.date.available2014-05-20T13:51:27Z
dc.date.issued2005-10-01
dc.description.abstractPurpose: To determine, in dogs anesthetized with nitrous oxide (N2O), whether the endotracheal tube (ETT) cuffed with a Lanz® pressure regulating valve decreases the tracheal consequences of tracheal intubation. Methods: Sixteen mixed-breed dogs were allocated to two groups according to the ETT used: Control group (n = 8) - Rüsch ETT, and Lanz group (n = 8) - ETT with Lanz® pressure regulating valve. The ETT cuffs in both groups were inflated with air to an intracuff pressure of 30 cm H2O. Anesthesia was induced and maintained with pentobarbitone and N2O (1.5 L·min-1) and O2 (1 L·min-1). ETT cuff pressures were measured before (control) and 60, 120, and 180 min during N2O administration. The dogs were sacrificed, and biopsy specimens from four predetermined areas of the tracheal mucosa in contact with the ETT were collected for light and scanning electron microscopy (SM) examination. Results: Cuff pressures in the Control group were higher than in the Lanz group at all time points studied (P < 0.001), with an increase over time only in the Control group (P < 0.001). Median neutrophilic inflammatory infiltration values of the epithelial surface, and in the subepithelial layer in contact with the cuff, were higher in the Control group as compared to the Lanz group (3.0 vs 1.0 and 3.0 vs 1.5 respectively) (P < 0.05). On SM examination, median histological grades were higher in the Control group compared to Lanz group (2.9 vs 1.9 respectively), (P < 0.05). Conclusions: The Lanz® ETT decreases tracheal mucosal injury in dogs.en
dc.description.affiliationUniv Estadual Paulista Julio Mesquita Filho, Sch Med, BR-18618970 Botucatu, SP, Brazil
dc.description.affiliationUniv Estadual Paulista Julio Mesquita Filho, Inst Biosci, Dept Morphol, BR-18618970 Botucatu, SP, Brazil
dc.description.affiliationUniv São Paulo, Sch Med, Dept Anesthesiol, BR-05508 São Paulo, Brazil
dc.description.affiliationUniv São Paulo, Sch Med, Dept Otorhinolaryngol, BR-05508 São Paulo, Brazil
dc.description.affiliationUniv São Paulo, Sch Med, Dept Ophthalmol & Head, BR-05508 São Paulo, Brazil
dc.description.affiliationUniv São Paulo, Sch Med, Dept Neck Surg, BR-05508 São Paulo, Brazil
dc.description.affiliationFed Univ Triangulo Mineiro, Sch Med, Dept Pathol, Uberaba, MG, Brazil
dc.description.affiliationUnespUniv Estadual Paulista Julio Mesquita Filho, Sch Med, BR-18618970 Botucatu, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista Julio Mesquita Filho, Inst Biosci, Dept Morphol, BR-18618970 Botucatu, SP, Brazil
dc.format.extent878-882
dc.identifierhttp://link.springer.com/article/10.1007%2FBF03021785
dc.identifier.citationCanadian Journal of Anesthesia, v. 52, n. 8, p. 878-882, 2005.
dc.identifier.doi10.1007/BF03021785
dc.identifier.issn0832-610X
dc.identifier.scopus2-s2.0-28444449161
dc.identifier.urihttp://hdl.handle.net/11449/130457
dc.identifier.wosWOS:000233024300016
dc.language.isoeng
dc.publisherCanadian Anesthesiologists Soc
dc.relation.ispartofCanadian Journal of Anesthesia
dc.relation.ispartofjcr3.377
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectCisatracurium
dc.subjectNitrous oxide
dc.subjectPentobarbital
dc.subjectInhalation anesthetic agent
dc.subjectAnesthesia induction
dc.subjectAnimal experiment
dc.subjectAnimal model
dc.subjectBiomedical technology assessment
dc.subjectControlled study
dc.subjectDog
dc.subjectEndotracheal intubation
dc.subjectEndotracheal tube
dc.subjectEpithelium
dc.subjectFemale
dc.subjectInflammatory infiltrate
dc.subjectMale
dc.subjectNeutrophil
dc.subjectNonhuman
dc.subjectPriority journal
dc.subjectScanning electron microscopy
dc.subjectTrachea injury
dc.subjectTrachea mucosa
dc.subjectTracheal biopsy
dc.subjectAnimal
dc.subjectAtmospheric pressure
dc.subjectInhalation anesthesia
dc.subjectInjury
dc.subjectInstrumentation
dc.subjectLarynx
dc.subjectLarynx mucosa
dc.subjectPathology
dc.subjectTrachea
dc.subjectAir Pressure
dc.subjectAnesthesia, Inhalation
dc.subjectAnesthetics, Inhalation
dc.subjectAnimals
dc.subjectDogs
dc.subjectEpithelium
dc.subjectFemale
dc.subjectIntubation, Intratracheal
dc.subjectLaryngeal Mucosa
dc.subjectLarynx
dc.subjectMale
dc.subjectMicroscopy, Electron, Scanning
dc.subjectNitrous Oxide
dc.subjectTrachea
dc.titleThe Lanz® endotracheal tube decreases tracheal injury in dogsen
dc.typeArtigo
dcterms.licensehttp://www.springer.com/open+access/authors+rights
dcterms.rightsHolderCanadian Anesthesiologists Soc
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatupt

Arquivos

Coleções

Artigos - Morfologia - IBB