Logotipo do repositório
 

Publicação:
Myelodysplastic syndrome in childhood: report of two cases with deletion of chromosome 4 and the Philadelphia chromosome

Página do item simplificado
dc.contributor.authorDalla Torre, C. A.
dc.contributor.authorLee, MLD
dc.contributor.authorYoshimoto, M.
dc.contributor.authorLopes, L. F.
dc.contributor.authorNiéro-Melo, Ligia [UNESP]
dc.contributor.authorde Toledo, SRC
dc.contributor.authorAndrade, JAD
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T15:20:35Z
dc.date.available2014-05-20T15:20:35Z
dc.date.issued2002-06-01
dc.description.abstractWe report two pediatric patients with unclassified myelodysplastic syndrome (MDS) by the French-American-British (FAB) group. Both cases had clinical and hematological peculiarities, which had not been described yet. The cytogenetic alterations were 4q deletion and the Philadelphia (Ph) chromosome which appeared at different moments of the disease. One patient showed the Ph chromosome at disease transformation and the other at diagnosis. The different breakpoints at 4q and the presence of Ph could be a marker of this form of MDS. The association of clinical and hematological findings suggests the possibility of a new group of pediatric MDS. (C) 2002 Elsevier B.V. Ltd. All rights reserved.en
dc.description.affiliationUniv Fed São Paulo, EPM, Dept Morphol, Discipline Genet, BR-04023900 São Paulo, Brazil
dc.description.affiliationUniv Fed São Paulo, EPM, GRAACC, Inst Oncol Pediat, BR-04023900 São Paulo, Brazil
dc.description.affiliationHosp AC Carmargo Fundação Antonio Prudente, Dept Pediat, São Paulo, Brazil
dc.description.affiliationUniv Estadual Paulista Julio Mesquita Filho, Fac Med, Dept Hematol, Botucatu, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista Julio Mesquita Filho, Fac Med, Dept Hematol, Botucatu, SP, Brazil
dc.format.extent533-538
dc.identifierhttp://dx.doi.org/10.1016/S0145-2126(01)00152-7
dc.identifier.citationLeukemia Research. Oxford: Pergamon-Elsevier B.V., v. 26, n. 6, p. 533-538, 2002.
dc.identifier.doi10.1016/S0145-2126(01)00152-7
dc.identifier.issn0145-2126
dc.identifier.urihttp://hdl.handle.net/11449/31858
dc.identifier.wosWOS:000175972700003
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofLeukemia Research
dc.relation.ispartofjcr2.319
dc.relation.ispartofsjr1,063
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectmyelodysplastic syndromept
dc.subjectPhiladelphia chromosomept
dc.subjectchromosome 4pt
dc.subjectdeletionpt
dc.subjectcytogeneticpt
dc.subjectFAB grouppt
dc.titleMyelodysplastic syndrome in childhood: report of two cases with deletion of chromosome 4 and the Philadelphia chromosomeen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderElsevier B.V.
dspace.entity.typePublication
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina, Botucatupt
unesp.departmentClínica Médica - FMBpt

Arquivos

Licença do Pacote

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:

Coleções

Botucatu - FMB - Faculdade de Medicina