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Publicação:
Biologically Active Eremophilane-Type Sesquiterpenes from Camarops sp., an Endophytic Fungus Isolated from Alibertia macrophylla

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dc.contributor.authorGubiani, Juliana R. [UNESP]
dc.contributor.authorZeraik, Maria L. [UNESP]
dc.contributor.authorOliveira, Camila M.
dc.contributor.authorXimenes, Valdecir F. [UNESP]
dc.contributor.authorNogueira, Claudio R. [UNESP]
dc.contributor.authorFonseca, Luiz M. [UNESP]
dc.contributor.authorSilva, Dulce Helena Siqueira [UNESP]
dc.contributor.authorBolzani, Vanderlan da Silva [UNESP]
dc.contributor.authorAraújo, Angela Regina [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal do Amazonas (UFAM)
dc.date.accessioned2014-12-03T13:11:29Z
dc.date.available2014-12-03T13:11:29Z
dc.date.issued2014-03-01
dc.description.abstractTwo new eremophilane-type sesquiterpenes, xylarenones F (3) and G (4), have been isolated from solid substrate cultures of a Camarops sp. endophytic fungus isolated from Alibertia macrophylla, together with the known compounds xylarenones C (1) and D (2). The structures and relative configurations of 1-4 were elucidated by extensive NMR and HRESIMS spectroscopic analysis. Due to their effects on the respiratory burst of neutrophils, which included inhibition of the reactive oxygen species production, these sesquiterpenes exhibited potential anti-inflammatory and antioxidant properties.en
dc.description.affiliationUniv Estadual Paulista, Dept Quim Organ, NuBBE Nucleo Bioensaios Biossintese & Ecofisiol P, Inst Quim, BR-14800900 Sao Paulo, Brazil
dc.description.affiliationUniv Fed Amazonas, Inst Ciencias Exatas & Tecnol, Itacoatiara, Amazonas, Brazil
dc.description.affiliationUniv Estadual Paulista, UNESP, Fac Ciencias, Dept Quim, BR-17033360 Bauru, SP, Brazil
dc.description.affiliationUniv Estadual Paulista, Fac Ciencias Farmaceut Araraquara, UNESP, Dept Anal Clin, BR-14801902 Araraquara, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Dept Quim Organ, NuBBE Nucleo Bioensaios Biossintese & Ecofisiol P, Inst Quim, BR-14800900 Sao Paulo, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, UNESP, Fac Ciencias, Dept Quim, BR-17033360 Bauru, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Fac Ciencias Farmaceut Araraquara, UNESP, Dept Anal Clin, BR-14801902 Araraquara, SP, Brazil
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipBiodiversity Virtual Institute Program
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipIdBiodiversity Virtual Institute Program03/02176-7
dc.format.extent668-672
dc.identifierhttp://dx.doi.org/10.1021/np400825s
dc.identifier.citationJournal Of Natural Products. Washington: Amer Chemical Soc, v. 77, n. 3, p. 668-672, 2014.
dc.identifier.doi10.1021/np400825s
dc.identifier.issn0163-3864
dc.identifier.lattes4702004904231248
dc.identifier.orcid0000-0001-7616-9652
dc.identifier.orcid0000-0002-1516-7765
dc.identifier.urihttp://hdl.handle.net/11449/113199
dc.identifier.wosWOS:000333662700034
dc.language.isoeng
dc.publisherAmer Chemical Soc
dc.relation.ispartofJournal of Natural Products
dc.relation.ispartofjcr3.885
dc.relation.ispartofsjr1,368
dc.rights.accessRightsAcesso restritopt
dc.sourceWeb of Science
dc.titleBiologically Active Eremophilane-Type Sesquiterpenes from Camarops sp., an Endophytic Fungus Isolated from Alibertia macrophyllaen
dc.typeArtigopt
dcterms.rightsHolderAmer Chemical Soc
dspace.entity.typePublication
relation.isDepartmentOfPublicationa83d26d6-5383-42e4-bb3c-2678a6ddc144
relation.isDepartmentOfPublication.latestForDiscoverya83d26d6-5383-42e4-bb3c-2678a6ddc144
relation.isOrgUnitOfPublication95697b0b-8977-4af6-88d5-c29c80b5ee92
relation.isOrgUnitOfPublication.latestForDiscovery95697b0b-8977-4af6-88d5-c29c80b5ee92
unesp.author.lattes4702004904231248[7]
unesp.author.lattes0037579054083160[9]
unesp.author.orcid0000-0001-7616-9652[9]
unesp.author.orcid0000-0002-1516-7765[7]
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Química, Araraquarapt
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Ciências Farmacêuticas, Araraquarapt
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Ciências, Baurupt
unesp.departmentQuímica - FCpt
unesp.departmentAnálises Clínicas - FCFpt
unesp.departmentQuímica Orgânica - IQARpt

Arquivos

Coleções

Araraquara - IQAR - Instituto de Química
Araraquara - FCF - Faculdade de Ciências Farmacêuticas
Bauru - FC - Faculdade de Ciências