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Synthesis and thermal study of the prodrug of oxamniquine

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Springer

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Abstract

Oxamniquine polymeric prodrug with potential antischistosomal activity was prepared using dextran T-70 as a carrier, which was analysed by (HNMR)-H-1, C-13 NMR and IR spectroscopy. The formation of the oxamniquine salt was confirmed by thermogravimetric analysis (TG) and differential scanning calorimetry (DSC) which showed a different thermal behaviour when compared to the physical mixture.

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DSC, oxamniquine, prodrug, TG

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English

Citation

Journal of Thermal Analysis and Calorimetry. Dordrecht: Springer, v. 83, n. 2, p. 277-281, 2006.

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Instituto de Química
IQAR
Campus: Araraquara


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