Enteric parasitic infections in children and dogs in resource-poor communities in northeastern Brazil: Identifying priority prevention and control areas

Abstract

Author summary The maintenance of high prevalence of enteric parasitic diseases in human and animal populations is an indisputable fact in the current scientific context. Despite all the advances in ecology, pathology, epidemiology and treatment, the control of these diseases remains ineffective and is a major problem in public health management. New control strategies should be tested in order to optimize the actions of current preventive programs and thus reduce prevalence. These strategies should include identification and mapping of geopolitical areas experiencing a greater frequency and overlap of enteric parasitic infections, and they must include the prevalence in both canine and human populations. This study indicates that poverty is strongly associated with the parasite's frequency. In a One Health approach, it demonstrates that affirmative actions of citizenship and income can be preventive health measures, and it also demonstrates the areas in which deworming actions must be a priority through control actions based on risk. The aim of this study was to determine the prevalence and risk factors of the main enteric parasitic infections that affect children and dogs in the municipality of Ilheus, Bahia, Brazil; and to identify the geopolitical areas that should receive priority interventions to combat them. Between March and November 2016, fecal samples of 143 dogs and 193 children aged 1 month to 5 years were collected in 40 rural and semirural communities using a systematic sampling approach, stratified by district. Samples were collected by legal guardians of the children and / or dog owners. Eggs, larvae, cysts and oocysts of parasites were concentrated by centrifugal-flotation and centrifugal-sedimentation, and acid-resistant staining was used to visualize parasites. One hundred and thirty-two children (68.4%), 111 dogs (77.6%) and 199 (73.7%) dog fecal samples collected from streets were parasitized. Giardiasis, cryptosporidiosis, amoeba infections and hookworm were the most frequent infections in all studied populations, in addition to trichuriasis in dogs and ascaridiasis in children. A predominance of Giardia and hookworms was observed in children and dogs, respectively. The coastal districts of Aritagua, Olivenca and the main district had a higher parasitic diversity and overlapping of important potential zoonotic infections. Age over one year (p<0.001), adjusted OR = 3.65; 95% CI = 1.86-7.16) and income below the minimum monthly salary (p = 0.02, adjusted OR = 2.78, 95% CI = 1.17-6.59) were the main factors associated with intestinal parasitic infections in children and dogs, respectively. The coastal districts of Aritagua and Olivenca and the main district should be prioritized through enteric disease control programs, and the factors associated with infections must be considered in the design of health interventions in these districts. The integration between affirmative income actions and investments to improve the health infrastructure of these communities may work more effectively than current preventive measures to combat enteric parasites.