Informamos que as validações de submissão estarão suspensas de 20/12/2019 a 05/01/2020, devido ao recesso de final de ano
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Now showing items 11-20 of 218
The Effects of 6% Hydroxyethyl Starch-Hypertonic Saline in Resuscitation of Dogs with Hemorrhagic Shock
(Anesthesia and Analgesia, 2011-02-01) [Artigo]
BACKGROUND: Hemodynamic and global oxygen transport variables have failed to reflect splanchnic hypoperfusion, resulting in a failure to recognize inadequately treated hemorrhagic shock. Volemic expansion after fluid ...
The possible role of selenium status in adverse pregnancy outcomes
(British Journal of Nutrition, 2011-05-01) [Artigo]
The present study reviews the possible role of Se status during pregnancy regarding adverse pregnancy outcomes, with emphasis on those related to diminished antioxidant activity and increased oxidative stress. Studies have ...
Vitamin C partially attenuates male reproductive deficits in hyperglycemic rats
(Reproductive Biology and Endocrinology, 2011-07-27) [Artigo]
Background: Hyperglycemia can impair the male reproductive system in experimental animals and in men during reproductive age. Studies have shown that vitamin C has some good effects on male reproductive system, and therefore ...
Diuron-induced rat urinary bladder carcinogenesis: Mode of action and human relevance evaluations using the International Programme on Chemical Safety framework
(Critical Reviews In Toxicology, 2014-05-01) [Artigo]
Diuron, a high volume substituted urea herbicide, induced high incidences of urinary bladder carcinomas and low incidences of kidney pelvis papillomas and carcinomas in rats exposed to high doses (2500 ppm) in a 2-year ...
Diuron metabolites and urothelial cytotoxicity: In vivo, in vitro and molecular approaches
(Toxicology, 2013-12-15) [Artigo]
Diuron is carcinogenic to the rat urinary bladder at high dietary levels. The proposed mode of action (MOA) for diuron is urothelial cytotoxicity and necrosis followed by regenerative urothelial hyperplasia. Diuron-induced ...
Caffeic Acid Phenethyl Ester Effects in the Kidney During Ischemia and Reperfusion in Rats Anesthetized with Isoflurane
(Transplantation Proceedings, 2012-06-01) [Artigo]
Background. The purpose of this investigation was to examine the effect of caffeic acid phenethyl ester (CAPE) in renal ischemia/reperfusion injury in rats anesthetized with isoflurane (iso).Methods. We randomly assigned ...
The central repeat domain 1 of Kaposi's sarcoma-associated herpesvirus (KSHV) latency associated-nuclear antigen 1 (LANA1) prevents cis MHC class I peptide presentation
(Virology, 2011-04-10) [Artigo]
KSHV LANA1, a latent protein expressed during chronic infection to maintain a viral genome, inhibits major histocompatibility complex class I (MHCI) peptide presentation in cis as a means of immune evasion. Through deletional ...
Maintaining Tissue Perfusion in High-Risk Surgical Patients: A Systematic Review of Randomized Clinical Trials
(Anesthesia and Analgesia, 2011-06-01) [Artigo]
BACKGROUND: Surgical patients with limited organic reserve are considered high-risk patients and have an increased perioperative mortality. For this reason, they need a more rigorous perioperative protocol of hemodynamic ...
Wavelet-based algorithm to the evaluation of contrasted hepatocellular carcinoma in CT-images after transarterial chemoembolization
(Radiation Oncology, 2014-07-26) [Artigo]
Background: Hepatocellular carcinoma is a primary tumor of the liver and involves different treatment modalities according to the tumor stage. After local therapies, the tumor evaluation is based on the mRECIST criteria, ...
Metalloproteinases 2 and-9 activity during promotion and progression stages of rat liver carcinogenesis
(Journal of Molecular Histology, 2009-02-01) [Artigo]
Activity of metalloproteinases 2 and 9 (MMP-2 and 9) during promotion and progression of rat liver carcinogenesis was investigated in a modified resistant hepatocyte model. Development of preneoplastic liver lesions positive ...