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The Effects of 6% Hydroxyethyl Starch-Hypertonic Saline in Resuscitation of Dogs with Hemorrhagic Shock
(Anesthesia and Analgesia, 2011-02-01) [Artigo]
BACKGROUND: Hemodynamic and global oxygen transport variables have failed to reflect splanchnic hypoperfusion, resulting in a failure to recognize inadequately treated hemorrhagic shock. Volemic expansion after fluid ...
Comparison of oxidative stress in ASA physical status I patients scheduled for minimally invasive surgery under balanced or intravenous anesthesia
(Minerva Anestesiologica, 2013-09-01) [Artigo]
Background. The effects of anesthetics on inflammation and oxidative parameters, evaluated in patients without morbidities undergoing undergoing minor surgery, remain unknown. The present study aimed to investigate the ...
Cytokine Profile in Patients Undergoing Minimally Invasive Surgery with Balanced Anesthesia
(Inflammation, 2012-12-01) [Artigo]
Patients undergoing surgical procedure develop an inflammatory response due to surgical trauma that may be modulated by anesthetics. The aim of this study was to investigate the cytokine profile in the plasma of adult ...
DNA damage in patients who underwent minimally invasive surgery under inhalation or intravenous anesthesia
(Mutation Research: Genetic Toxicology and Environmental Mutagenesis, 2011-12-24) [Artigo]
Recent studies have demonstrated the genotoxicity of anesthetics in patients who have undergone surgery and in personnel who are occupationally exposed to anesthetics. However, these findings are controversial. Herein, we ...
Evaluation of DNA damage and lipoperoxidation of propofol in patients undergoing elective surgery
(European Journal of Anaesthesiology, 2009-08-01) [Artigo]
Background and objectives Inhaled anaesthetics have been studied regarding their genotoxic and mutagenic potential in vivo. Propofol differs from volatile anaesthetics because it does not show mutagenic effects and it has ...
Lower levels of oxidative DNA damage and apoptosis in lymphocytes from patients undergoing surgery with propofol anesthesia
(Environmental and Molecular Mutagenesis, 2012-01-01) [Artigo]
Propofol, which is widely used as an intravenous anesthetic, has a phenolic structure similar to that of a-tocopherol with antioxidant properties that could prevent genotoxicity and cytotoxicity in lymphocytes of anesthetized ...
Remifentanil, Isoflurane, and Preconditioning Attenuate Renal Ischemia/Reperfusion Injury in Rats
(Transplantation Proceedings, 2009-12-01) [Artigo]
Background: The purpose of this investigation was to examine the effect of isoflurane, remifentanil, and preconditioning in renal ischemia/reperfusion injury (IRI).Methods: M 52 male Wistar rats were anesthetized with ...
The Humidity in a Drager Primus Anesthesia Workstation Using Low or High Fresh Gas Flow and With or Without a Heat and Moisture Exchanger in Pediatric Patients
(Anesthesia And Analgesia, 2014-10-01) [Artigo]
BACKGROUND: An inhaled gas absolute humidity of 20 mg H2O.L-1 is the value most considered as the threshold necessary for preventing the deleterious effects of dry gas on the epithelium of the airways during anesthesia. ...
Does the Choice of the Halogenated Anesthetic Influence Renal Function during Hemorrhagic Shock and Resuscitation?
(Renal Failure, 2009-01-01) [Artigo]
Introduction. Halogenated anesthetics can cause changes in the variables that modify the cardiac output necessary to maintain renal hemodynamic during hemorrhagic shock and resuscitation. However, halogenated anesthetics ...
Genotoxicity, cytotoxicity and gene expression in patients undergoing elective surgery under isoflurane anaesthesia
(Mutagenesis, 2011-05-01) [Artigo]
There are numerous studies reporting on the effects of inhalation anaesthesia in cells of exposed individuals but not much is known about the ability of isoflurane (ISF) to induce oxidative DNA damage. However, surgery is ...