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Piperidinium derivatives including spectaline and cassine derivatives, pharmaceutic compositions containing the same and preparation process
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2010-02-26Type
Patent

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Disclosed are compounds of formulae (II) and (III), wherein R1 is other than hydrogen and the remaining substituents are as defined in the specification, processes for their preparation and pharmaceutical compositions containing them. The compounds are capable of inhibiting acetylcholinesterase, and are useful in the treatment of pathologies associated with cholinergic transmission, such as memory related disorders, neurodegenerative disorders such as Alzheimer's Disease, Myasthenia Gravis and intoxication induced by chemical agents.
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Viegas Junior, Cláudio et al Piperidinium derivatives including spectaline and cassine derivatives, pharmaceutic compositions containing the same and preparation process. Instituto Nacional de Propriedade Industrial (INPI), 2010. Available at: <http://hdl.handle.net/11449/109087>.
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