Piperidinium derivatives including spectaline and cassine derivatives, pharmaceutic compositions containing the same and preparation process
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Data
2010-02-26
Autores
Viegas Junior, Cláudio
Bolzani, Vanderlan da Silva [UNESP]
Barreiro, Eliezer Jesus de Lacerda
Castro, Newton G.
Young, Maria Claudia Marx
Rocha, Monica Santos
Fraga, Carlos Alberto Manssour
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Instituto Nacional de Propriedade Industrial (INPI)
Resumo
Disclosed are compounds of formulae (II) and (III), wherein R1 is other than hydrogen and the remaining substituents are as defined in the specification, processes for their preparation and pharmaceutical compositions containing them. The compounds are capable of inhibiting acetylcholinesterase, and are useful in the treatment of pathologies associated with cholinergic transmission, such as memory related disorders, neurodegenerative disorders such as Alzheimer's Disease, Myasthenia Gravis and intoxication induced by chemical agents.
Descrição
Processo: NZ554392A
Número de publicação: NZ554392 (A)
Número de aplicação: NZ20040554392
Número de publicação: NZ554392 (A)
Número de aplicação: NZ20040554392