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dc.contributor.authorMoura, Regina [UNESP]
dc.contributor.authorYoshida, Winston Bonetti [UNESP]
dc.contributor.authorFabris, Viciany Erique [UNESP]
dc.contributor.authorAngeleli, AYO
dc.contributor.authorNaresse, Luiz Eduardo [UNESP]
dc.contributor.authorMaffei, Francisco Humberto de Abreu [UNESP]
dc.date.accessioned2014-05-20T13:32:19Z
dc.date.available2014-05-20T13:32:19Z
dc.date.issued2003-06-01
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/12865878
dc.identifier.citationInternational Angiology. Turin: Edizioni Minerva Medica, v. 22, n. 2, p. 134-140, 2003.
dc.identifier.issn0392-9590
dc.identifier.urihttp://hdl.handle.net/11449/11030
dc.description.abstractAim. Autologous vein (AV) is sometimes not suitable or present for a vascular restoration. Homologous vein preserved in glutaraldehyde may be an alternative to AV, but little is yet known about this graft and its healing process after implantation in arteries. The purpose of this study was to compare the initial healing process of glutaraldehyde-tanned homologous venous grafts (group 1) with fresh autologous venous grafts (group 2), at 4 or 15 days.Methods. Forty Norfolk rabbits were allocated in 2 groups of 20 animals each. The grafts was interposed in the infra-renal aorta of the rabbit. Anastomotic tensile strength (TS), hydroxyproline (HP) determination, and histology (HA) were performed.Results. TS increased in both groups, from the 4th to 15th day, (p < 0.01) in both proximal (G1: from 364.5 &PLUSMN; 98.3 g to 491.8 &PLUSMN; 107.3 g; G2: from 366.26 &PLUSMN; 85.15 g to 518.46 &PLUSMN; 82.79 g) and distal anastomosis (GI: from 363.53 &PLUSMN; 96.26 g to 507.32 &PLUSMN; 91.01 g; G2: from 352.30 &PLUSMN; 102.41 g to 528.67 &PLUSMN; 48.58 g), with no difference between the groups. HP did not change (p > 0.10) in this same period and was similar in both groups, in the proximal (GI: from 677.99 +/- 153.98 mug/100 mg to 914.92 +/- 459.83 mug/100 mg; G2: from 668.65 +/- 170.28 mug/100 mg to 669.46 +/- 319.80 mug/100 mg) as well as in the distal anastomosis (G1:from 740.07 +/- 213.53 mug/100 mg to 923.52 +/- 270.57 mug/100 mg; G2: from 737.66 +/- 266.76 mug/100 mg to 707.68 +/- 171.25 mug/100 mg). Initial inflammatory and reparative features of the anastomosis were similar in both groups.Conclusion. We can conclude that the healing process of the glutaraldehyde-tanned homologous vein graft was similar to that of the fresh autologous venous graft.en
dc.format.extent134-140
dc.language.isoeng
dc.publisherEdizioni Minerva Medica
dc.relation.ispartofInternational Angiology
dc.sourceWeb of Science
dc.subjectwound healingpt
dc.subjectveinspt
dc.subjectglutaralpt
dc.subjectrabbitspt
dc.subjectbioprosthesispt
dc.subjecttensile strengthpt
dc.subjecthydroxyprolinept
dc.titleHealing process in anastomosis of homologous venous grafts preserved in glutaraldehyde implanted aorta of rabbitsen
dc.typeArtigo
dcterms.rightsHolderEdizioni Minerva Medica
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.description.affiliationUniv Estadual Paulista, Dept Cirurgia & Ortopedia, Fac Med Botucatu, Sch Med, BR-18618970 Botucatu, SP, Brazil
dc.description.affiliationUniv Estadual Paulista, Dept Pathol, Sch Med, BR-18618970 Botucatu, SP, Brazil
dc.description.affiliationUniv Estadual Paulista, Dept Med, Sch Med, BR-18618970 Botucatu, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Dept Cirurgia & Ortopedia, Fac Med Botucatu, Sch Med, BR-18618970 Botucatu, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Dept Pathol, Sch Med, BR-18618970 Botucatu, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Dept Med, Sch Med, BR-18618970 Botucatu, SP, Brazil
dc.identifier.wosWOS:000184273300004
dc.rights.accessRightsAcesso restrito
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina, Botucatupt
dc.identifier.lattes3613835231654932
dc.identifier.lattes4880803690413862
dc.identifier.lattes3769255547738283
unesp.author.lattes3613835231654932
unesp.author.lattes4880803690413862
unesp.author.lattes3769255547738283
dc.relation.ispartofjcr1.156
dc.relation.ispartofsjr0,476
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