Departamento de Clínica Médica
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Recent Submissions
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Cardiac Remodeling: Concepts, Clinical Impact, Pathophysiological Mechanisms and Pharmacologic Treatment
(Arquivos brasileiros de cardiologia, 2016) [Resenha]Cardiac remodeling is defined as a group of molecular, cellular and interstitial changes that manifest clinically as changes in size, mass, geometry and function of the heart after injury. The process results in poor ... -
Safety of the effective radiation dose received during stroke hospitalization
(Jornal Vascular Brasileiro, 2021) [Artigo]Background: Neuroimaging is widely used for diagnosis and treatment of stroke. However, little is known about whether the radiation doses received by patients comply with international safety guidelines. Objectives: The ... -
Treating Inflammation Associated with Pulmonary Hypertension: An Overview of the Literature
(International Journal of General Medicine, 2022) [Artigo]Pulmonary hypertension (PH) comprises five groups of serious clinical entities characterized by pulmonary artery vasoconstriction and vascular remodeling leading to right heart failure and death. In addition to vascular ... -
Prediction of Non-canonical Routes for SARS-CoV-2 Infection in Human Placenta Cells
(Frontiers in Molecular Biosciences, 2021) [Artigo]The SARS-CoV-2 is the causative agent of the COVID-19 pandemic. The data available about COVID-19 during pregnancy have demonstrated placental infection; however, the mechanisms associated with intrauterine transmission ... -
L-carnitine supplementation in the diabetic heart
(Arquivos Brasileiros de Cardiologia, 2021) [Editorial] -
Peritoneal dialysis modality transition and impact on phosphate and potassium serum levels
(PLoS ONE, 2021) [Artigo]Peritoneal dialysis (PD) modalities affect solute removal differently. However, the impacts of switching PD modalities on serum levels of biomarkers of different sizes are not known. Our objective was to analyze whether a ... -
Relationship between innate immune response toll-like receptor 4 (Tlr-4) and the pathophysiological process of obesity cardiomyopathy
(Arquivos Brasileiros de Cardiologia, 2021) [Artigo]Background: Obesity is a chronic low-grade inflammation condition related to cardiac disorders. However, the mechanism responsible for obesity-related cardiac inflammation is unclear. The toll-like receptor 4 (TLR-4) belongs ... -
Clinical trials in cardiac xenotransplantation: Are we ready to overcome barriers?
(Journal of Cardiac Surgery, 2021) [Resenha]Heart allotransplantation has become one of the methods of choice in the treatment of severe heart failure. In the face of its difficulties, such as the unmet balance between organ supply and demand, the use of xenotransplantation ... -
The Impact of Age on Mortality and Disability in Patients With Ischemic Stroke Who Underwent Cerebral Reperfusion Therapy: A Brazilian Cohort Study
(Frontiers in Aging Neuroscience, 2021) [Artigo]Introduction: The main driver for increased stroke prevalence is the aging of the population; however, the best evidenced-based strategies for stroke treatment and prevention are not always followed for older patients. ... -
Effects of obesity on the cardiac proteome
(Endocrine and Metabolic Science, 2021) [Artigo]Obesity has reached epidemic proportions in both developed and developing countries. It is currently recognized as a major health concern due to excessive adipose tissue which is associated with a wide range of other medical ... -
Emergence and persistence of high-risk clones among MDR and XDR A. baumanniiat a Brazilian teaching hospital
(Frontiers in Microbiology, 2019) [Artigo]Dissemination of carbapenem-resistant Acinetobacter baumannii is currently one of the priority themes discussed around the world, including in Brazil, where this pathogen is considered endemic. A total of 107 carbapenem-resistant ... -
AT1 receptor blockade attenuates insulin resistance and myocardial remodeling in rats with diet-induced obesity
(PLoS ONE, 2014) [Artigo]Background: Although obesity has been associated with metabolic and cardiac disturbances, the carrier mechanisms for these responses are poorly understood. This study analyzed whether angiotensin II blockade attenuates ... -
Fase 0, fase I em pesquisa clínica e o registro de publicações
(Brazilian Journal of Cardiovascular Surgery, 2013) [Carta] -
Clinical and laboratory evaluation of hyperlipemic and hypothyroid patients
(Arquivos Brasileiros de Cardiologia, 2001) [Artigo]Objective - To determine the frequency of hypothyroidism in a sample of hyperlipemicpatients and evaluate clinical and laboratory factors indicative of thyropathy among them. Methods - Fifty-one hyperlipemic patients, ... -
Upregulation of mRNA myocardium calcium handling in rats submitted to exercise and food restriction
(Arquivos Brasileiros de Cardiologia, 2011) [Artigo]Background: Chronic exercise and food restriction (FR) have directionally opposite changes in transcription of molecular structures of calcium handling and thyroid hormone (TH) status. Objective: Evaluate the association ... -
Hypertrophied myocardium is more dependent on extracellular calcium than the normal cardiac muscle
(Case Reports and Clinical Practice Review, 2010) [Artigo]Background: The aim of this study was to analyze stable hypertrophied myocardial function and its response to inotropic maneuvers in rats submitted to renovascular hypertension for a 10-week period (RHT group, n=10). ... -
Insuficiência cardíaca com fração de ejeção normal
(Arquivos Brasileiros de Cardiologia, 2010) [Resenha]Heart failure with normal ejection fraction (HFNEF) is a complex syndrome that has been broadly studied since the last decade. It is caused by diastolic ventricular dysfunction demonstrated by complementary methods, such ... -
Factors contributing to the differences in peritonitis rates between centers and regions
(Peritoneal Dialysis International, 2007) [Trabalho apresentado em evento]Despite improvements in connectology, peritoneal dialysis (PD)-associated peritonitis contributes significantly to morbidity and modality failure in patients maintained on PD therapy. A broad spectrum of organisms - ... -
Comparação de diferentes métodos para medida do tamanho do infarto experimental crônico em ratos
(Arquivos Brasileiros de Cardiologia, 2007) [Artigo]Objective: To evaluate the differences between three methods for the measurement of experimental infarction in rats in comparison to the traditional method. Methods: Histological analysis of the infarction area (AREA), ... -
Influências de dietas ricas em ácidos graxos saturados e insaturados sobre o miocárdio de ratos
(Arquivos Brasileiros de Cardiologia, 2007) [Artigo]Objectives: To study the influence of saturated (SFA) and unsaturated fatty acid (UFA) rich diets on mechanical function, morphology and oxidative stress in rat myocardium. Methods: Male, 60-day-old Wistar rats were fed a ...