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dc.contributor.authorAlvarez, Matheus [UNESP]
dc.contributor.authorMiranda, Diana Rodrigues de Pina [UNESP]
dc.contributor.authorOliveira, Marcela de [UNESP]
dc.contributor.authorRibeiro, Sergio Marrone [UNESP]
dc.contributor.authorMendes, Rinaldo Poncio [UNESP]
dc.contributor.authorDuarte, Sergio B.
dc.contributor.authorMiranda, Jose R. A. [UNESP]
dc.date.accessioned2015-03-18T15:54:44Z
dc.date.available2015-03-18T15:54:44Z
dc.date.issued2014-11-01
dc.identifierhttp://dx.doi.org/10.1097/MD.0000000000000167
dc.identifier.citationMedicine. Philadelphia: Lippincott Williams & Wilkins, v. 93, n. 25, 6 p., 2014.
dc.identifier.issn0025-7974
dc.identifier.urihttp://hdl.handle.net/11449/117018
dc.description.abstractThis study presents methodology for objectively quantifying the pulmonary region affected by emphysemic and fibrotic sequelae in treated patients with paracoccidioidomycosis. This methodology may also be applied to any other disease that results in these sequelae in the lungs.Pulmonary high-resolution computed tomography examinations of 30 treated paracoccidioidomycosis patients were used in the study. The distribution of voxel attenuation coefficients was analyzed to determine the percentage of lung volume that consisted of emphysemic, fibrotic, and normal tissue. Algorithm outputs were compared with subjective evaluations by radiologists using a scale that is currently used for clinical diagnosis.Affected regions in the patient images were determined by computational analysis and compared with estimates by radiologists, revealing mean (+/- standard deviation) differences in the scores for fibrotic and emphysemic regions of 0.1% +/- 1.2% and +/- 0.2% +/- 1.0%, respectively.The computational results showed a strong correlation with the radiologist estimates, but the computation results were more reproducible, objective, and reliable.en
dc.description.sponsorshipHC-FMB
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.format.extent6
dc.language.isoeng
dc.publisherLippincott Williams & Wilkins
dc.relation.ispartofMedicine
dc.sourceWeb of Science
dc.titleObjective CT-Based Quantification of Lung Sequelae in Treated Patients With Paracoccidioidomycosisen
dc.typeArtigo
dcterms.rightsHolderLippincott Williams & Wilkins
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionCBPF MCT
dc.description.affiliationUniv Estadual Paulista, Dept Fis & Biofis, Inst Biociencias Botucatu, Sao Paulo, Brazil
dc.description.affiliationUniv Estadual Paulista, Dept Doencas Trop & Diagnost Imagem, Fac Med Botucatu, Sao Paulo, Brazil
dc.description.affiliationCBPF MCT, Ctr Brasileoro Pesquisas Fis, Brasilia, DF, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Dept Fis & Biofis, Inst Biociencias Botucatu, Sao Paulo, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Dept Doencas Trop & Diagnost Imagem, Fac Med Botucatu, Sao Paulo, Brazil
dc.identifier.doi10.1097/MD.0000000000000167
dc.identifier.wosWOS:000345559000010
dc.rights.accessRightsAcesso restrito
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Biociências, Botucatupt
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina, Botucatupt
unesp.author.orcid0000-0002-8306-8056[7]
dc.relation.ispartofjcr2.028
dc.relation.ispartofsjr0,799
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