Exercise improves immune function, antidepressive response, and sleep quality in patients with chronic primary insomnia
Carregando...
Data
2014-01-01
Autores
Passos, Giselle Soares
Poyares, Dalva
Santana, Marcos Goncalves
Souza Teixeira, Alexandre Abilio de
Lira, Fabio Santos [UNESP]
Youngstedt, Shawn D.
Thomatieli dos Santos, Ronaldo Vagner
Tufik, Sergio
Mello, Marco Tulio de
Título da Revista
ISSN da Revista
Título de Volume
Editor
Hindawi Publishing Corporation
Resumo
The aim of this study was to evaluate the effects of moderate aerobic exercise training on sleep, depression, cortisol, and markers of immune function in patients with chronic primary insomnia. Twenty-one sedentary participants (16 women aged 44.7 +/- 9 years) with chronic primary insomnia completed a 4-month intervention of moderate aerobic exercise. Compared with baseline, polysomnographic data showed improvements following exercise training. Also observed were reductions in depression symptoms and plasma cortisol. Immunologic assays revealed a significant increase in plasma apolipoprotein A (140.9 +/- 22 to 151.2 +/- 22mg/dL) and decreases in CD4 (915.6 +/- 361 to 789.6 +/- 310 mm(3)) and CD8 (532.4 +/- 259 to 435.7 +/- 204 mm(3)). Decreases in cortisol were significantly correlated with increases in total sleep time (r. = -0.51) and REMsleep (r. = -0.52). In summary, long-termmoderate aerobic exercise training improved sleep, reduced depression and cortisol, and promoted significant changes in immunologic variables.
Descrição
Palavras-chave
Como citar
Biomed Research International. New York: Hindawi Publishing Corporation, 7 p., 2014.