Nanotechnology-based drug delivery systems for treatment of oral cancer: a review
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Data
2014-01-01
Autores
Calixto, Giovana [UNESP]
Bernegossi, Jessica [UNESP]
Fonseca-Santos, Bruno [UNESP]
Chorilli, Marlus [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Dove Medical Press Ltd
Resumo
Oral cancer (oral cavity and oropharynx) is a common and aggressive cancer that invades local tissue, can cause metastasis, and has a high mortality rate. Conventional treatment strategies, such as surgery and chemoradiotherapy, have improved over the past few decades; however, they remain far from optimal. Currently, cancer research is focused on improving cancer diagnosis and treatment methods (oral cavity and oropharynx) nanotechnology, which involves the design, characterization, production, and application of nanoscale drug delivery systems. In medicine, nanotechnologies, such as polymeric nanoparticles, solid lipid nanoparticles, nanostructured lipid carriers, gold nanoparticles, hydrogels, cyclodextrin complexes, and liquid crystals, are promising tools for diagnostic probes and therapeutic devices. The objective of this study is to present a systematic review of nanotechnology-based drug delivery systems for oral cancers.
Descrição
Palavras-chave
targeted delivery, oral squamous cell carcinoma, oral cancer treatment
Como citar
International Journal Of Nanomedicine. Albany: Dove Medical Press Ltd, v. 9, p. 3719-3735, 2014.