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Altered distribution of peripheral blood dendritic cell subsets in patients with pulmonary paracoccidioidomycosis
Venturini, James
; Cavalcante, Ricardo Souza ; ; Golim, Márjorie de Assis ; Levorato, Adriele Dandara ; Reis, Karoline Hagatha dos ; Arruda, Maria Sueli Parreira de ; Mendes, Rinaldo Poncio (Acta Tropica, 2017) [Artigo]
Paracoccidioidomycosis (PCM) is a systemic mycosis caused by fungi from the genus Paracoccidioides in Latin America. PCM-patients (PCM-p) are classified as having acute/subacute or chronic (CF) clinical forms. CF is ... -
Body Composition and Metabolic Syndrome Components on Lipodystrophy Different Subtypes Associated with HIV
Sacilotto, Livia Bertazzo; Pereira, Paulo Câmara Marques ; ; Papini, Sílvia Justina (Journal of Nutrition and Metabolism, 2017) [Artigo]
HIV-associated lipodystrophy syndrome (HALS) is characterized by body fat redistribution as a consequence of the antiretroviral therapy (ART) introduction, associated with an increased risk of cardiovascular disease ... -
Imbalanced Macrophage and Dendritic Cell Activations in Response to Candida albicans in a Murine Model of Diabetes Mellitus
Venturini, James; Fraga-Silva, Thais Fernanda Campos ; Marchetti, Camila Martins ; Mimura, Luiza Ayumi Nishiyama ; Conti, Bruno José ; Golim, Márjorie de Assis ; Mendes, Rinaldo Poncio ; de Arruda, Maria Sueli Parreira (Immunological Investigations, 2016) [Artigo]
Bloodstream infections caused by Candida species are responsible for high morbidity and mortality, and diabetes mellitus (DM) is an important underlying disease in candidemia episodes. Although DM patients show an enhanced ... -
The first postoperative-stimulated serum thyroglobulin is a prognostic factor for thyroid microcarcinomas
(Brazilian Journal of Otorhinolaryngology, 2017) [Artigo]Introduction: Endogenous thyroid-stimulating hormone-stimulated thyroglobulin collected after total thyroidectomy is a useful predictor of better prognosis in patients with differentiated thyroid carcinomas in general, but ... -
Post-discharge impact of healthcare-associated infections in a developing country: A cohort study
De Souza, Emília Carolina Oliveira; Ferreira Filho, Sebastião Pires ; Gervatauskas, Kasys Meira ; Fortaleza, Carlos Magno Castelo Branco (Infection Control and Hospital Epidemiology, 2018) [Artigo]
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Which of the branched-chain amino acids increases cerebral blood flow in hepatic encephalopathy? A double-blind randomized trial
Romeiro, Fernando Gomes; Ietsugu, Marjorie do Val ; Franzoni, Letícia de Campos ; Augusti, Laís ; Alvarez, Matheus ; Santos, Lívia Alves Amaral ; Lima, Talles Bazeia ; Koga, Kátia Hiromoto ; Moriguchi, Sônia Marta ; Caramori, Carlos Antonio et al. (NeuroImage: Clinical, 2018) [Artigo]
Branched-chain amino acids increase the brain perfusion of patients with hepatic encephalopathy (HE), but the amino acid and the mechanisms involved are still unknown. This study compared brain perfusion and clinical ... -
Nasal colonization with methicillin-resistant Staphylococcus aureus among elderly living in nursing homes in Brazil: Risk factors and molecular epidemiology
da Silveira, Monica; Cunha, Maria de Lourdes Ribeiro de Souza ; de Souza, Camila Sena Martins ; Correa, Adriana Aparecida Feltrin ; Fortaleza, Carlos Magno Castelo Branco (Annals of Clinical Microbiology and Antimicrobials, 2018) [Artigo]
Background: Methicillin-resistant Staphylococcus aureus poses a threat to elderly living in nursing homes. Studies focusing on the epidemiology of colonization may help in the design of infection control strategies. ... -
Cryptococcus neoformans and gattii promote DNA damage in human peripheral blood mononuclear cells
Andrade, Jéssica Cristina Bilizario Noguerol; Gatto, Mariana ; Rodrigues, Daniela Ramos ; De Campos Soares, Ângela Maria Victoriano ; Calvi, Sueli Aparecida (Medical Mycology, 2018) [Artigo]
Cryptococcosis, a systemic mycosis capable of disseminating to the central nervous system with frequent lethal effects, is caused by the species Cryptococus neoformans and Cryptococcus gattii. Several infectious agents ... -
Detection of the mecA gene and identification of Staphylococcus directly from blood culture bottles by multiplex polymerase chain reaction
Rocchetti, Taisa Trevizani; Martins, Katheryne Benini ; Martins, Patricia Yoshida Faccioli ; Oliveira, Rogério Antonio de ; Mondelli, Alessandro Lia ; Fortaleza, Carlos Magno Castelo Branco ; Cunha, Maria de Lourdes Ribeiro de Souza da (Brazilian Journal of Infectious Diseases, 2018) [Artigo]
Introduction: Staphylococcus spp. – both S. aureus, including methicillin-resistant strains (MRSA) and coagulase negative staphylococci (CoNS) – are relevant agents of healthcare-associated infections. Therefore, the rapid ... -
Ischemic stroke enhancement using a variational model and the expectation maximization method
Alves, Allan Felipe Fattori; ; de Miranda, José Ricardo Arruda ; de Freitas, Carlos Clayton Macedo ; ; de Pina, Diana Rodrigues (European Radiology, 2018) [Artigo]
Objectives: In order to enable less experienced physicians to reliably detect early signs of stroke, A novel approach was proposed to enhance the visual perception of ischemic stroke in non-enhanced CT. Methods: A set of ... -
Molecular detection of fungi of public health importance in wild animals from Southern Brazil
Losnak, Debora O.; ; ; ; ; ; ; ; ; et al. (Mycoses, 2018) [Artigo]
Some animals have an important relationship with fungal infections, and searching for pathogens in animal samples may be an opportunity for eco-epidemiological research. Since studies involving wildlife are generally ... -
Paracoccidioidomycosis: Current perspectives from Brazil
Mendes, Rinaldo Poncio; Cavalcante, Ricardo de Souza ; Marques, Sílvio Alencar ; Marques, Mariângela Esther Alencar ; Venturini, James ; Sylvestre, Tatiane Fernanda ; ; ; da Silva, Julhiany de Fátima ; Fabro, Alexandre Todorovic et al. (Open Microbiology Journal, 2017) [Resenha]
Background: This review article summarizes and updates the knowledge on paracoccidioidomycosis. P lutzii and the cryptic species of P. brasiliensis and their geographical distribution in Latin America, explaining the ... -
Nucleic acid amplification techniques (NAATs) for early diagnosis of HIV-1 and HIV-2 infections
El Dib, Regina; ; ; Almeida, Ricardo A.M.B. ; ; ; Müller, Sergio S. ; (Cochrane Database of Systematic Reviews, 2015) [Artigo]
This is the protocol for a review and there is no abstract. The objectives are as follows: Our primary objective is to assess the diagnostic accuracy (sensitivity and specificity) of NAATs (both quantitative and qualitative) ... -
Molecular identification and phylogenetic analysis of Bothrops insularis bacterial and fungal microbiota
Barbosa, Lidiane Nunes; Ferreira, Rui Seabra ; Luiza Mello, Priscila ; Garcia Garces, Hans ; Luana Chechi, Jéssica ; Frachin, Tarsila ; De Barros, Luciana Curtolo ; De Moraes Guimenes Bosco, Sandra ; Bagagli, Eduardo ; Fernandes Júnior, Ary et al. (Journal of Toxicology and Environmental Health - Part A: Current Issues, 2018) [Artigo]
Bothrops insularis, known as the golden lancehead snake, has its natural habitat restricted to Queimada Grande Island on the southern coast of Brazil. This culture-dependent study aimed to identify microorganisms obtained ... -
Benznidazole affects expression of Th1, Th17 and Treg cytokines during acute experimental Trypanosoma cruzi infection
Gatto, Mariana; Oliveira, Larissa Ragozo Cardoso ; De Nuzzi Dias, Fernanda ; Araújo Júnior, João Pessoa ; Lima, Carlos Roberto Gonçalves ; ; dos Santos, Rodrigo Mattos ; Kurokawa, Cilmery Suemi (Journal of Venomous Animals and Toxins Including Tropical Diseases, 2017) [Artigo]
Background: The present study evaluated the effect of treatment with benznidazole on mRNA expression of IFN-γ, IL-17, IL-10, TGF-β and FoxP3 in spleen and heart tissue of BALB/c mice in the acute phase of an experimental ... -
Crotalus durissus terrificus crotapotin naturally displays preferred positions for amino acid substitutions
de Oliveira, Laudicéia Alves; Ferreira, Rui Seabra ; Barraviera, Benedito ; de Carvalho, Francilene Capel Tavares ; de Barros, Luciana Curtolo ; dos Santos, Lucilene Delazari ; Pimenta, Daniel Carvalho (Journal of Venomous Animals and Toxins Including Tropical Diseases, 2017) [Artigo]
Background: Classically, Crotalus durissus terrificus (Cdt) venom can be described, according to chromatographic criteria, as a simple venom, composed of four major toxins, namely: gyroxin, crotamine, crotoxin and convulxin. ... -
Detection of Leishmania spp. using parasitological, serological and molecular assays in asymptomatic and sick cats from an endemic area of visceral leishmaniosis in Brazil
Alves-Martin, Maria Fernanda; Paixão, Mirian dos Santos ; ; Tenório, Michely da Silva ; ; Starke-Buzetti, Wilma Aparecida ; ; Lucheis, Simone Baldini (Asian Pacific Journal of Tropical Disease, 2017) [Artigo]
Objective: To analyze the prevalence of feline leishmaniosis in 55 asymptomatic cats or assess clinical disease in a visceral leishmaniasis-endemic area using parasitological, serological and molecular techniques. Methods: ... -
Multiple Lacunar Infarcts in Paroxysmal Nocturnal Hemoglobinuria
Meira, Alex Tiburtino; ; Trindade, André Petean ; Bazan, Silméia Garcia Zanati ; Braga, Gabriel Pereira ; Bazan, Rodrigo (Journal of Stroke and Cerebrovascular Diseases, 2017) [Artigo]
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired disease characterized by clonal hematopoietic stem cell disorder, with increased mortality and morbidity. Venous thrombosis is the most common cause of mortality ... -
Plasma proteome of buffaloes
de Pontes, Leticia Gomes; Cavassan, Nayara Rodrigues Vieira ; de Barros, Luciana Curtolo ; Ferreira Junior, Rui Seabra ; Barraviera, Benedito ; Santos, Lucilene Delazari dos (Proteomics - Clinical Applications, 2017) [Artigo]
The proteomic approach has aroused the interest of veterinary medicine researchers, especially regarding the production of biopharmaceuticals and diagnosis of diseases in farm animals. Water buffaloes have gained prominence ... -
Use of parenteral antimicrobials in very small hospitals in inner Brazil: patterns, determinants, and opportunities for interventions in developing countries
Giacomini, J. L.; Fortaleza, C. M. (Journal of Hospital Infection, 2017) [Artigo]
Much of healthcare in developing countries takes place in small hospitals. Little is known about the use of antimicrobials in those settings. We studied the 60-day use of parenteral antimicrobials in 48 hospitals with up ...