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dc.contributor.authorCalderon, Iracema de Mattos Paranhos [UNESP]
dc.contributor.authorDamasceno, Débora Cristina [UNESP]
dc.contributor.authorAmorin, Renee L.
dc.contributor.authorCosta, Roberto Antonio de Araújo [UNESP]
dc.contributor.authorBrasil, Maria A. M.
dc.contributor.authorRudge, Marilza Vieira Cunha [UNESP]
dc.date.accessioned2014-05-20T13:35:04Z
dc.date.available2014-05-20T13:35:04Z
dc.date.issued2007-10-01
dc.identifierhttp://dx.doi.org/10.1016/j.diabres.2007.01.023
dc.identifier.citationDiabetes Research and Clinical Practice. Clare: Elsevier B.V., v. 78, n. 1, p. 65-71, 2007.
dc.identifier.issn0168-8227
dc.identifier.urihttp://hdl.handle.net/11449/12027
dc.description.abstractIn this study, morphometric measures of placental terminal villi and villous vessels were compared in overt, as well as gestational diabetes mellitus, and mild hyperglycemia diagnosed by oral 100 g glucose tolerance test (100 g-OGTT) and glucose profile (GP). At delivery (gestational age >= 34 weeks) a total of 207 placentas were assigned to a control group (n = 56) or to one of three groups complicated by mild hyperglycemia (n = 5 1), gestational diabetes (n = 59) and overt diabetes (n = 4 1). Placenta samples were randomly selected for blind morphometric assessment with an image analyser. Morphometric measures obtained included area and number of terminal villi and their respective villous vessels. Statistical analyses were performed using the chi-square test, ANOVA and stepwise regression (p <= 0.05). Glycemic means were 86.2 mg/dL in controls, 98.9 mg/dL in mild hyperglycemia, 114.1 mg/dL in gestational diabetes and 122.1 mg/dL in overt diabetes. Our results show that abnormal maternal glycemic levels may change the placental morphometric characteristics related to materno-fetal exchanges. (C) 2007 Elsevier B.V.. All rights reserved.en
dc.format.extent65-71
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofDiabetes Research and Clinical Practice
dc.sourceWeb of Science
dc.subjectdiabetespt
dc.subjecthyperglycemiapt
dc.subjectplacentapt
dc.subjectmorphometrypt
dc.titleMorphometric study of placental villi and vessels in women with mild hyperglycemia or gestational or overt diabetesen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderElsevier B.V.
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.description.affiliationUniv Estadual Paulista, Botucatu Med Sch, Dept Obstet & Gynecol, Diabet & Pregnancy Serv, São Paulo, Brazil
dc.description.affiliationUniv Estadual Paulista, Sch Vet Med Botucatu, Dept Pathol, São Paulo, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Botucatu Med Sch, Dept Obstet & Gynecol, Diabet & Pregnancy Serv, São Paulo, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Sch Vet Med Botucatu, Dept Pathol, São Paulo, Brazil
dc.identifier.doi10.1016/j.diabres.2007.01.023
dc.identifier.wosWOS:000250130500011
dc.rights.accessRightsAcesso restrito
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina, Botucatupt
dc.identifier.lattes0679387622604743
dc.identifier.lattes6758680388835078
dc.identifier.orcid0000-0002-9227-832X
unesp.author.lattes0679387622604743
unesp.author.lattes6758680388835078
unesp.author.orcid0000-0003-4761-4336[1]
unesp.author.orcid0000-0002-9227-832X[6]
dc.relation.ispartofjcr2.548
dc.relation.ispartofsjr1,538
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