Departamento de Neurologia, Psicologia e Psiquiatria
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Recent Submissions
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Oral Colonization by Candida Species in Patients with Multiple Sclerosis
(Mycopathologia, 2020) [Artigo]Introduction: Multiple sclerosis (MS) is a chronic inflammatory demyelinating autoimmune disease that affects the central nervous system. Since immune system plays a key role in this disease, patients with MS can present ... -
Endocannabinoid neuromodulation in the neostriatum decreases the GABAergic striato-nigral disinhibitory function and increases the nigro-collicular inhibitory pathway activity
(Journal of Neural Transmission, 2020) [Artigo]We previously reported the involvement of neostriato-nigral projections in the organisation of innate fear and panic attack-like responses organised by dorsal midbrain neurons, such as the periaqueductal grey matter and ... -
Early diagnosis and treatment of Alzheimer’s disease: New definitions and challenges
(Brazilian Journal of Psychiatry, 2020) [Artigo]The prevalence of Alzheimer’s disease (AD), a progressive neurodegenerative disorder, is expected to more than double by 2050. Studies on the pathophysiology of AD have been changing our understanding of this disorder and ... -
Cognitive impairment in remitted late-life depression is not associated with Alzheimer's disease-related CSF biomarkers
(Journal of Affective Disorders, 2020) [Artigo]Background: Cognitive impairment is a common feature of late-life depression (LLD). Early studies using Alzheimer's disease (AD) biomarkers inferred a biological link between AD pathology and LLD, but recent findings have ... -
Passive antiamyloid immunotherapy for Alzheimer's disease
(Current Opinion in Psychiatry, 2020) [Resenha]Purpose of reviewAntiamyloid therapy of Alzheimer's disease tackles the overproduction and clearance of the amyloid-beta peptide (Aβ). Immunotherapeutic compounds were tested in large-scale trials. We revisit the recent ... -
Low-Intensity Photobiomodulation Decreases Neuropathic Pain in Paw Ischemia-Reperfusion and Spared Nervus Ischiadicus Injury Experimental Models
(Pain Practice, 2020) [Artigo]Background: There is a wide range of animal models available today for studying chronic pain associated with a variety of etiologies and an extensive list of clinical manifestations of peripheral neuropathies. Photobiomodulation ... -
Cross-cultural adaptation and validation for the Brazilian population of the instrument Amyotrophic Lateral Sclerosis-Specific Quality of Life–Short Form (ALSSQOL-SF)
(Quality of Life Research, 2020) [Artigo]Objective: This study aims to produce and validate the version of the instrument Amyotrophic Lateral Sclerosis-Specific Quality of Life–Short Form (ALSSQOL-SF) into Portuguese, adapted to the Brazilian cultural context. ... -
A Brazilian multicentre study evaluating pregnancies induced by cabergoline in patients harboring prolactinomas
(Pituitary, 2020) [Artigo]Objective: To evaluate the maternal–fetal outcomes of CAB-induced pregnancies in patients with prolactinoma in a large cohort. Methods: The prevalence of tumor growth, miscarriage, preterm, low birth weight, congenital ... -
Can MoCA and MMSE Be Interchangeable Cognitive Screening Tools? A Systematic Review
(Gerontologist, 2019) [Resenha]Background and Objectives: Cognitive disorders may be an early sign of neuropsychiatric disorders; however, it remains unclear whether the screening measures are interchangeable. The aim of this study was to contrast the ... -
Long-term follow-up of patients undergoing decompressive hemicraniectomy for malignant stroke: Quality of life and caregiver's burden in a real-world setting
(Clinical Neurology and Neurosurgery, 2020) [Artigo]Background and Purpose: Decompressive hemicraniectomy is a life-saving procedure for the treatment of space-occupying middle cerebral artery infarctions (malignant stroke); however, patients may survive severely disabled. ... -
Could Differences in Infection Pressure Be Involved in Cysticercosis Heterogeneity?
(Trends in Parasitology, 2020) [Resenha]The presentation of cysticercosis is very heterogeneous both between and within countries. Several host and parasite factors are involved in this heterogeneity. Differences in the intensity of infection pressure have not ... -
Social losses predict a faster onset and greater severity of obsessive-compulsive disorder
(Journal of Psychiatric Research, 2020) [Artigo]Background: While stressful life events increase the risk of developing a range of psychiatric disorders, including obsessive-compulsive disorder (OCD), their ability to precipitate specific obsessive-compulsive symptoms' ... -
Children’s anxiety and factors related to the covid-19 pandemic: An exploratory study using the children’s anxiety questionnaire and the numerical rating scale
(International Journal of Environmental Research and Public Health, 2020) [Artigo]The repercussions of the COVID-19 pandemic on children’s lives deserve attention. This study aimed to assess the prevalence of anxiety among Brazilian children and its associated factors during social distancing during ... -
Alcohol use and risk of vehicle accidents: Cross-sectional study in the city of São Paulo, Brazil
(Sao Paulo Medical Journal, 2020) [Artigo]BACKGROUND: Harm to other people caused by an individual under the influence of alcohol (UIA) can occur in a variety of relationship situations between the drinker and these other people. OBJECTIVES: To estimate the ... -
COVID-19 in people with multiple sclerosis: A global data sharing initiative
(Multiple Sclerosis Journal, 2020) [Artigo]Background: We need high-quality data to assess the determinants for COVID-19 severity in people with MS (PwMS). Several studies have recently emerged but there is great benefit in aligning data collection efforts at a ... -
Translation of a Brazilian educational booklet concerning hydrocephalus into Spanish as spoken in Spain
(Revista Cientifica de la Sociedad Espanola de Enfermeria Neurologica, 2020) [Artigo]Purpose: A booklet for children with hydrocephalus and their parents was presented. This study translated the Brazilian version of the booklet “Laura's diary: knowing hydrocephalus and its treatment” into Spanish as spoken ... -
Strain pattern and T-wave alterations are predictors of mortality and poor neurologic outcome following stroke
(Clinical Cardiology, 2020) [Artigo]Background: Stroke is associated with electrocardiogram (ECG) abnormalities. However, the role of strain pattern as predictor of poor neurologic outcome and mortality after stroke has not yet been demonstrated. Hypothesis: ... -
Quantile graphs for EEG-based diagnosis of Alzheimer’s disease
(PLoS ONE, 2020) [Artigo]Known as a degenerative and progressive dementia, Alzheimer’s disease (AD) affects about 25 million elderly people around the world. This illness results in a decrease in the productivity of people and places limits on ... -
Caregivers’ evaluation of an educational material targeted to children with hydrocephalus
(Child's Nervous System, 2020) [Artigo]Purpose: Modern pediatric neurosurgery succeeded in reducing ventricle-peritoneal shunt malfunctions and shunt revisions. However, some children may be submitted to many surgeries, posing burden to their caregivers. And ... -
Evaluating Educational Material from the Perspective of Informal Caregivers of Children with Hydrocephalus: A Qualitative Study
(World Neurosurgery, 2020) [Artigo]Objective: We evaluated whether educational material about hydrocephalus and its treatment previously developed by health professionals corresponded with the daily life of caregivers of children with hydrocephalus. Methods: ...