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dc.contributor.authorRosa, Ana Carolina
dc.contributor.authorDiniz, Juliana Belo
dc.contributor.authorFossaluza, Victor
dc.contributor.authorTorres, Albina Rodrigues [UNESP]
dc.contributor.authorFontenelle, Leonardo Franklin
dc.contributor.authorDe Mathis, Alice Simoes
dc.contributor.authorRosario, Maria da Conceicao
dc.contributor.authorMiguel, Euripedes Constantino
dc.contributor.authorShavitt, Roseli Gedanke
dc.identifier.citationJournal of Psychiatric Research. Oxford: Pergamon-Elsevier B.V. Ltd, v. 46, n. 10, p. 1286-1292, 2012.
dc.description.abstractBackground: Patients with obsessive-compulsive disorder (OCD) frequently show poor social adjustment, which has been associated with OCD severity. Little is known about the effects that age at symptom onset, specific OCD symptoms, and psychiatric comorbidities have on social adjustment. The objective of this study was to investigate the clinical correlates of social functioning in OCD patients.Methods: Cross-sectional study involving 815 adults with a primary DSM-IV diagnosis of OCD participating in the Brazilian Research Consortium on Obsessive-Compulsive Spectrum Disorders. Patients were assessed with the Social Adjustment Scale, the Medical Outcomes Study 36-item Short-Form Health Survey, the Yale-Brown Obsessive-Compulsive Scale, the Dimensional Yale-Brown Obsessive-Compulsive Scale, and the Structured Clinical Interview for DSM-IV Axis I Disorders. Clinical correlates of social adjustment were assessed with generalized linear models with gamma distribution.Results: Poor overall social functioning was associated with greater OCD severity (p = 0.02); hoarding symptoms (p = 0.004); sexual/religious obsessions (p = 0.005); current major depressive disorder (p = 0.004); current post-traumatic stress disorder (p = 0.002); and current eating disorders (p = 0.02). Poor social adjustment was also associated with impaired quality of life.Conclusions: Patients with OCD have poor social functioning in domains related to personal relationships and professional performance. Hoarding symptoms and sexual/religious obsessions seem to have the strongest negative effects on social functioning. Early age at OCD symptom onset seems to be associated with professional and academic underachievement and impairment within the family unit, whereas current psychiatric comorbidity worsen overall social functioning. In comparison with quality of life, social adjustment measures seem to provide a more comprehensive overview of the OCD-related burden. (C) 2012 Elsevier Ltd. All rights reserved.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.publisherPergamon-Elsevier B.V. Ltd
dc.relation.ispartofJournal of Psychiatric Research
dc.sourceWeb of Science
dc.subjectObsessive-compulsive disorderen
dc.subjectSocial functioningen
dc.subjectQuality of lifeen
dc.subjectPsychiatric disordersen
dc.titleClinical correlates of social adjustment in patients with obsessive-compulsive disorderen
dcterms.rightsHolderPergamon-Elsevier B.V. Ltd
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionUniversidade Federal do Rio de Janeiro (UFRJ)
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.description.affiliationUniv São Paulo, Sch Med, Hosp Clin, Dept & Inst Psychiat, São Paulo, Brazil
dc.description.affiliationUniv São Paulo, Math & Stat Inst, São Paulo, Brazil
dc.description.affiliationSão Paulo State Univ, Botucatu Sch Med, Dept Neurol Psychol & Psychiat, Botucatu, SP, Brazil
dc.description.affiliationUniv Fed Rio de Janeiro, Inst Psychiat, Program Anxiety & Depress, Rio de Janeiro, Brazil
dc.description.affiliationUniv Fed São Paulo, Dept Psychiat, São Paulo, Brazil
dc.description.affiliationUnespSão Paulo State Univ, Botucatu Sch Med, Dept Neurol Psychol & Psychiat, Botucatu, SP, Brazil
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dc.description.sponsorshipIdFAPESP: 08/57780-0
dc.description.sponsorshipIdFAPESP: 06/50273-0
dc.description.sponsorshipIdFAPESP: 05/55628-8
dc.description.sponsorshipIdFAPESP: 06/61459
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina, Botucatupt
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