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dc.contributor.authorSoares, Diana Gabriela de Souza [UNESP]
dc.contributor.authorPontes, Elaine Cristina Voltolini [UNESP]
dc.contributor.authorRibeiro, Ana Paula Dias
dc.contributor.authorBasso, Fernanda Gonçalves [UNESP]
dc.contributor.authorHebling, Josimeri [UNESP]
dc.contributor.authorCosta, Carlos Alberto de Souza [UNESP]
dc.date.accessioned2015-08-06T16:12:11Z
dc.date.available2015-08-06T16:12:11Z
dc.date.issued2013
dc.identifierhttp://www.amjdent.com/previousarticles.htm
dc.identifier.citationAmerican Journal of Dentistry, v. 26, p. 283-285, 2013.
dc.identifier.issn0894-8275
dc.identifier.urihttp://hdl.handle.net/11449/125476
dc.description.abstractTo assess the trans-enamel and trans-dentin toxicity of a 10% hydrogen peroxide (HP) whitening strip to odontoblast-like cells (MDPC-23). Methods: Enamel surfaces of enamel/dentin discs adapted to artificial pulp chambers were subjected to two 30-minute whitening strip applications to obtain indirect extracts (DMEM + bleaching components that diffused across enamel and dentin). The extracts were applied for 1 hour to the cells for 1 or 5 days. A bleaching gel with 35% HP was used as the positive control. Cell viability (MTT assay) and morphology (SEM) as well as the quantity of HP in the extracts were assessed. Results: Discrete cell viability reduction (21.9%) associated with slight alterations in cell morphology occurred after application of the extracts for 5 days to the MDPC-23 cells (Tukey's test; P< 0.05). Lower enamel/dentin diffusion of HP was observed after the use of the whitening strip compared with the bleaching gel (Mann-Whitney; P< 0.05).en
dc.description.sponsorshipFundacao de Amparo a Pesquisa do Estado de sao Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)
dc.format.extent283-285
dc.language.isoeng
dc.relation.ispartofAmerican Journal of Dentistry
dc.sourceCurrículo Lattes
dc.subjectRandomized clinical-trialen
dc.subjectBleaching gelen
dc.subjectIn-vitroen
dc.subjectPeroxide penetrationen
dc.subjectCarbamide peroxideen
dc.subjectHydrogen-peroxideen
dc.subjectMdpc-23 cellsen
dc.subjectEfficacyen
dc.subjectOfficeen
dc.subjectProductsen
dc.titleLow toxic effects of a whitening strip to cultured pup cellsen
dc.typeArtigo
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionUniversidade de Brasília (UnB)
dc.description.affiliationUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Clínica Infantil, Faculdade de Odontologia de Araraquara, Araraquara, Rua Humaitá, 1680, Centro, CEP 14801-903, SP, Brasil
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Clínica Infantil, Faculdade de Odontologia de Araraquara, Araraquara, Rua Humaitá, 1680, Centro, CEP 14801-903, SP, Brasil
dc.rights.accessRightsAcesso restrito
dc.description.sponsorshipIdFAPESP: 2011/12938-8
dc.description.sponsorshipIdFAPESP: 2011/09385-7
dc.description.sponsorshipIdCNPq: 301029/2010-1
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Odontologia, Araraquarapt
dc.identifier.lattes1531215699841687
dc.identifier.lattes5087114843448227
dc.identifier.lattes8207097271172991
dc.identifier.lattes4517484241515548
unesp.departmentFisiologia e Patologiapt
unesp.departmentMateriais Odontológicos e Prótesept
unesp.departmentClínica Infantilpt
unesp.author.lattes1531215699841687
unesp.author.lattes5087114843448227
unesp.author.lattes8207097271172991
unesp.author.lattes4517484241515548
dc.relation.ispartofjcr0.760
dc.relation.ispartofsjr0,509
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