Sulcus vocalis: evidence for autosomal dominant inheritance
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Data
2011-01-01
Autores
Martins, Regina Helena Garcia [UNESP]
Goncalves, T. M. [UNESP]
Neves, D. S. [UNESP]
Fracalossi, T. A. [UNESP]
Tavares, E. L. M. [UNESP]
Moretti-Ferreira, D. [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Funpec-editora
Resumo
We found evidence of autosomal dominant hereditary transmission of sulcus vocalis. Four dysphonic patients from three generations of the same family were submitted to videolaryngoscopic examination (three patients) and to direct laryngoscopy ( one patient) to diagnose the hoarseness. Sulcus vocalis was diagnosed in all four patients. The finding of four affected individuals in three generations, with vertical transmission affecting man and women, is more consistent with autosomal dominant inheritance pattern; it is an etiological model that we propose for the sulcus vocalis in this pedigree.
Descrição
Palavras-chave
Autosomal dominant, Sulcus vocalis, Hoarseness, Videolaryngoscopy, Genetics, Laryngeal development
Como citar
Genetics and Molecular Research. Ribeirao Preto: Funpec-editora, v. 10, n. 4, p. 3163-3168, 2011.