Now showing items 1-10 of 62
Citrus aurantium L. essential oil exhibits anxiolytic-like activity mediated by 5-HT1A-receptors and reduces cholesterol after repeated oral treatment
(BMC Complementary and Alternative Medicine, 2013-02-23) [Artigo]
Background: The current treatments for anxiety disorders and depression have multiple adverse effects in addition to a delayed onset of action, which has prompted efforts to find new substances with potential activity in ...
Cytotoxic action of Brazilian propolis in vitro on canine osteosarcoma cells
(Phytotherapy Research, 2013-09-01) [Artigo]
Osteosarcoma (OSA) is a primary bone neoplasm frequently diagnosed in dogs. The biology of OSA in pet dogs is identical to that of pediatric patients, and it has been considered an excellent model in vivo to study human ...
Comparison of oxidative stress in ASA physical status I patients scheduled for minimally invasive surgery under balanced or intravenous anesthesia
(Minerva Anestesiologica, 2013-09-01) [Artigo]
Background. The effects of anesthetics on inflammation and oxidative parameters, evaluated in patients without morbidities undergoing undergoing minor surgery, remain unknown. The present study aimed to investigate the ...
Macrophage activity and histopathology of the lymphohematopoietic organs in male Wistar rats orally exposed to single or mixed pesticides
(Journal of Environmental Science and Health - Part B: Pesticides, Food Contaminants, and Agricultural Wastes, 2013-07-01) [Artigo]
The noxious effects of low or effective dose exposure to single or mixed pesticides on macrophage activity and the lymphohematopoietic organs were investigated. Male Wistar rats were orally exposed to dichlorvos, dicofol, ...
Indole-3-carbinol attenuates the deleterious gestational effects of bisphenol A exposure on the prostate gland of male F1 rats
(Reproductive Toxicology, 2014-01-01) [Artigo]
Bisphenol A (BPA) is a chemical that has been investigated for it potential to cause prostate diseases. In this study, pregnant Sprague-Dawley rats were treated with 25 or 250 mu g/kg BPA from gestational day (GD) 10 to ...
EFFECTS of DIURON on MALE RAT REPRODUCTIVE ORGANS: A DEVELOPMENTAL and POSTNATAL STUDY
(Journal of Toxicology and Environmental Health: Part A Current Issues, 2012-01-01) [Artigo]
This study was performed to determine whether developmental exposure (perinatal and juvenile) to the herbicide diuron exerted adverse effects on adult rat male reproductive system. Pregnant Sprague-Dawley rats received ...
Human neutrophils produce IL-12, IL-10, PGE2 and LTB4 in response to Paracoccidioides brasiliensis. Involvement of TLR2, mannose receptor and dectin-1
(Cytokine, 2014-05-01) [Artigo]
The functions of phagocytic cells against pathogens are initiated by the interaction between membrane receptors and molecular structures which compose the cell wall of these microorganisms. Thus our study aimed to identify ...
Immunomodulatory effects of low dose chemotherapy and perspectives of its combination with immunotherapy
(International Journal of Cancer, 2013-06-01) [Artigo]
Given that cancer is one of the main causes of death worldwide, many efforts have been directed toward discovering new treatments and approaches to cure or control this group of diseases. Chemotherapy is the main treatment ...
Decreased Sperm Motility in Rats Orally Exposed to Single or Mixed Pesticides
(Journal of Toxicology and Environmental Health: Part A Current Issues, 2010-01-01) [Artigo]
The Brazilian Agency of Sanitary Vigilance (ANVISA) conducted a study that demonstrated the presence of residues of several pesticides in fresh fruits and vegetables that were available for purchase by the general populace. ...
Late Stage of Experimental Pulmonary Fibrosis is Modulated by Collagen V
(Histopathology, 2012-10-01) [Resumo]