Now showing items 1-10 of 78
Inhibition of Mouse Urinary Bladder Carcinogenesis by A double dagger ai Fruit (Euterpe oleraceae Martius) Intake
(Plant Foods For Human Nutrition, 2012-09-01) [Artigo]
A double dagger ai, fruit from Euterpe oleraceae Martius, is consumed in natura and in a variety of beverages and food preparations and possesses several potential antioxidant compounds. In a first study for anticarcinogenicity ...
Screening for In Vitro and In Vivo Antitumor Activities of the Mushroom Agaricus Blazei
(Nutrition and Cancer-an International Journal, 2009-01-01) [Artigo]
We have investigated the in vitro antitumor activity of the mushroom Agaricus blazei Murill on human cancer cell lines as well as its potential anticancer activity in a model of rat colon carcinogenesis. The in vitro ...
Diuron-induced rat urinary bladder carcinogenesis: Mode of action and human relevance evaluations using the International Programme on Chemical Safety framework
(Critical Reviews In Toxicology, 2014-05-01) [Artigo]
Diuron, a high volume substituted urea herbicide, induced high incidences of urinary bladder carcinomas and low incidences of kidney pelvis papillomas and carcinomas in rats exposed to high doses (2500 ppm) in a 2-year ...
Diuron metabolites and urothelial cytotoxicity: In vivo, in vitro and molecular approaches
(Toxicology, 2013-12-15) [Artigo]
Diuron is carcinogenic to the rat urinary bladder at high dietary levels. The proposed mode of action (MOA) for diuron is urothelial cytotoxicity and necrosis followed by regenerative urothelial hyperplasia. Diuron-induced ...
The central repeat domain 1 of Kaposi's sarcoma-associated herpesvirus (KSHV) latency associated-nuclear antigen 1 (LANA1) prevents cis MHC class I peptide presentation
(Virology, 2011-04-10) [Artigo]
KSHV LANA1, a latent protein expressed during chronic infection to maintain a viral genome, inhibits major histocompatibility complex class I (MHCI) peptide presentation in cis as a means of immune evasion. Through deletional ...
Effectiveness of a 10-wk Lifestyle Modification Program in Reducing Hypertension in Brazilian Free-Living Adults
(Faseb Journal, 2017-04-01) [Resumo]
Metalloproteinases 2 and-9 activity during promotion and progression stages of rat liver carcinogenesis
(Journal of Molecular Histology, 2009-02-01) [Artigo]
Activity of metalloproteinases 2 and 9 (MMP-2 and 9) during promotion and progression of rat liver carcinogenesis was investigated in a modified resistant hepatocyte model. Development of preneoplastic liver lesions positive ...
Cell-free antigens from precocious Paracoccidioides brasiliensis culture induce a typical delayed-type hypersensitivity reaction
(Journal of Venomous Animals and Toxins Including Tropical Diseases, 2011-01-01) [Artigo]
Cell-free antigens (CFAg) derived from Paracoccidioides brasiliensis have typically been used in immunodiffusion reactions for serodiagnosis or therapeutic follow-up of paracoccidioidomycosis patients. Thus, we investigated ...
Human neutrophils produce IL-12, IL-10, PGE2 and LTB4 in response to Paracoccidioides brasiliensis. Involvement of TLR2, mannose receptor and dectin-1
(Cytokine, 2014-05-01) [Artigo]
The functions of phagocytic cells against pathogens are initiated by the interaction between membrane receptors and molecular structures which compose the cell wall of these microorganisms. Thus our study aimed to identify ...
Lack of Chemopreventive Activity of Agaricus blazei Mushroom on the Development of 1,2-Dimethylhydrazine-Induced Colonic Aberrant Crypt Foci in Rats
(Nutrition and Cancer-an International Journal, 2008-01-01) [Artigo]
Chemopreventive and immunomodulatory potential of methanolic (MET) and dichloromethanic (DCl) extracts of Agaricus blazei mushroom were investigated in the postinitiation stage of colon carcinogenesis in male Wistar rats. ...