Now showing items 1-10 of 16
Dose-response of diuron [3-(3,4-dichlorophenyl)-1,1-dimethylurea] in the urothelial mucosa of Wistar rats
(Toxicology, 2013-08-20) [Artigo]
Diuron [3-(3,4-dichlorophenyl)-1,1-dimethylurea] is a herbicide that induced urothelial tumors in the urinary bladder of Wistar rats fed 2500. ppm during a long-term study. The currently suggested non-genotoxic mode of ...
Diet-induced obesity impairs AKT signalling in the retina and causes retinal degeneration
(Cell Biochemistry and Function, 2013-01-01) [Artigo]
Retinopathy, a common complication of diabetes, is characterized by an unbalanced production of nitric oxide (NO), a process regulated by nitric oxide synthase (NOS). We hypothesized that retinopathy might stem from changes ...
Easiness of use and validity testing of VS-SENSE device for detection of abnormal vaginal flora and bacterial vaginosis
(Infectious Diseases in Obstetrics and Gynecology, 2010-11-22) [Artigo]
Accessing vaginal pH is fundamental during gynaecological visit for the detection of abnormal vaginal flora (AVF), but use of pH strips may be time-consuming and difficult to interpret. The aim of this study was to evaluate ...
Anticancer effects of geopropolis produced by stingless bees on canine osteosarcoma cells in vitro
(Evidence-based Complementary and Alternative Medicine, 2013-05-13) [Artigo]
Geopropolis is produced by indigenous stingless bees from the resinous material of plants, adding soil or clay. Its biological properties have not been investigated, such as propolis, and herein its cytotoxic action on ...
Lack of association between HLA-E polymorphisms and transitional cell carcinoma of the bladder
(Tissue Antigens, 2013-09-01) [Carta]
Morphologic and biomechanical changes of thoracic and abdominal aorta in a rat model of cigarette smoke exposure
(Annals of Vascular Surgery, 2013-08-01) [Artigo]
Background: Smoking is the most relevant environmental factor that affects the development of aortic aneurysm. Smokers have elevated levels of elastase activity in the arterial wall, which leads to weakening of the aorta. ...
DNA repair gene polymorphism is associated with the genetic basis of atherosclerotic coronary artery disease
(Cardiovascular Pathology, 2011-01-01) [Artigo]
Background: Atherosclerotic coronary artery disease (CAD) is a multifactorial process that appears to be caused by the interaction of environmental risk factors with multiple predisposing genes. It is nowadays accepted ...
Chromosomal imbalances in successive moments of human bladder urothelial carcinoma
(Urologic Oncology: Seminars and Original Investigations, 2013-08-01) [Artigo]
Objective: To understand developmental characteristics of urinary bladder carcinomas (UBC) by evaluating genomic alterations and p53 protein expression in primary tumors, their recurrences, and in the morphologically normal ...
Fine needle aspirate cell blocks are reliable for detection of hormone receptors and HER-2 by immunohistochemistry in breast carcinoma
(Cytopathology, 2013-02-01) [Artigo]
Aims: To evaluate the reliability of fine needle aspirate cell blocks in the assessment of oestrogen receptor (ER), progesterone receptor (PR) and HER-2/neu proteins by immunohistochemistry in comparison with surgical ...
Photodynamic therapy for the treatment of induced mammary tumor in rats
(Lasers in Medical Science, 2013-02-01) [Artigo]
The objective of this work was to evaluate photodynamic therapy (PDT) by using a hematoporphyrin derivative as a photosensitizer and light-emitting diodes (LEDs) as light source in induced mammary tumors of Sprague-Dawley ...