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Now showing items 1-10 of 16
Dose-response of diuron [3-(3,4-dichlorophenyl)-1,1-dimethylurea] in the urothelial mucosa of Wistar rats
(Toxicology, 2013-08-20) [Artigo]
Diuron [3-(3,4-dichlorophenyl)-1,1-dimethylurea] is a herbicide that induced urothelial tumors in the urinary bladder of Wistar rats fed 2500. ppm during a long-term study. The currently suggested non-genotoxic mode of ...
Immunomodulatory effects of low dose chemotherapy and perspectives of its combination with immunotherapy
(International Journal of Cancer, 2013-06-01) [Artigo]
Given that cancer is one of the main causes of death worldwide, many efforts have been directed toward discovering new treatments and approaches to cure or control this group of diseases. Chemotherapy is the main treatment ...
Previous contact with Strongyloides venezuelensis contributed to prevent insulitis in MLD-STZ diabetes
(Experimental Parasitology, 2013-06-01) [Artigo]
Epidemiological and experimental studies support the idea that helminth infections can induce a protective effect against the development of autoimmune and allergic diseases. In this study we characterized the immune ...
Diet-induced obesity impairs AKT signalling in the retina and causes retinal degeneration
(Cell Biochemistry and Function, 2013-01-01) [Artigo]
Retinopathy, a common complication of diabetes, is characterized by an unbalanced production of nitric oxide (NO), a process regulated by nitric oxide synthase (NOS). We hypothesized that retinopathy might stem from changes ...
Sialidase activity in aerobic vaginitis is equal to levels during bacterial vaginosis
(European Journal of Obstetrics & Gynecology and Reproductive Biology, 2013-04-01) [Artigo]
Objective: To evaluate levels of proinflammatory cytokines and sialidase activity in aerobic vaginitis (AV) in relation to normal vaginal flora and bacterial vaginosis (BV). Study design: In this cross-sectional study, a ...
Do Atopobium vaginae, Megasphaera sp. and Leptotrichia sp. change the local innate immune response and sialidase activity in bacterial vaginosis?
(Sexually Transmitted Infections, 2013-03-01) [Artigo]
Objectives: To investigate if the participation of Atopobium vaginae, Megasphaera sp. and Leptotrichia sp. in the bacterial community of bacterial vaginosis (BV) is associated with distinct patterns of this condition. ...
Anticancer effects of geopropolis produced by stingless bees on canine osteosarcoma cells in vitro
(Evidence-based Complementary and Alternative Medicine, 2013-05-13) [Artigo]
Geopropolis is produced by indigenous stingless bees from the resinous material of plants, adding soil or clay. Its biological properties have not been investigated, such as propolis, and herein its cytotoxic action on ...
Lack of association between HLA-E polymorphisms and transitional cell carcinoma of the bladder
(Tissue Antigens, 2013-09-01) [Carta]
Morphologic and biomechanical changes of thoracic and abdominal aorta in a rat model of cigarette smoke exposure
(Annals of Vascular Surgery, 2013-08-01) [Artigo]
Background: Smoking is the most relevant environmental factor that affects the development of aortic aneurysm. Smokers have elevated levels of elastase activity in the arterial wall, which leads to weakening of the aorta. ...
Clinical patterns and epidemiological characteristics of facial melasma in Brazilian women
(Journal of the European Academy of Dermatology and Venereology, 2013-02-01) [Artigo]
Background Melasma is a common acquired chronic hypermelanosis of sun-exposed areas which significantly impacts quality of life. There are few epidemiological studies in medical literature concerning these patients. Objective ...