Now showing items 11-20 of 44
Influence of diet on oxidative DNA damage, uracil misincorporation and DNA repair capability
(Mutagenesis, 2010-09-01) [Resumo]
The contribution of diet to cancer ranges from 10 to 80%. The low ingestion of antioxidants and enzymatic cofactors involved in DNA repair and methylation reactions and the high ingestion of chemical additives present in ...
MRE11A and SKP2 genes are associated with the increased cytotoxicity induced by the synergistic effects of cisplatin and gemcitabine in bladder cancer cells
(Molecular Biology Reports, 2014-07-01) [Artigo]
The combination of gemcitabine and cisplatin has been shown previously to elicit a synergistic therapeutic effect on bladder cancer cell lines and result in reduced cell survival. However, the precise mechanism by which ...
Cholesterol reduction and lack of genotoxic or toxic effects in mice after repeated 21-day oral intake of lemongrass (Cymbopogon citratus) essential oil
(Food and Chemical Toxicology, 2011-09-01) [Artigo]
Cymbopogon citratus (lemongrass) is currently used in traditional folk medicine. Although this species presents widespread use, there are no scientific data on its efficacy or safety after repeated treatments. Therefore, ...
Micronucleus cytome assay in potentially malignant lesions and oral cancer
(Oral Diseases, 2010-09-01) [Artigo]
Lower levels of oxidative DNA damage and apoptosis in lymphocytes from patients undergoing surgery with propofol anesthesia
(Environmental and Molecular Mutagenesis, 2012-01-01) [Artigo]
Propofol, which is widely used as an intravenous anesthetic, has a phenolic structure similar to that of a-tocopherol with antioxidant properties that could prevent genotoxicity and cytotoxicity in lymphocytes of anesthetized ...
Evaluation of area contaminated by wood treatment activities: genetic markers in the environment and in the child population
(Chemosphere, 2015) [Artigo]
Wood preservation activities and related compounds are a problem since these areas have major environmental contamination liabilities which compromise the health of the surrounding population and the integrity of ecological ...
Transcriptional Alterations in the SOD2 Gene Is Not Related to the Newborn Obesity Predisposition.
(Environmental And Molecular Mutagenesis, 2014-09-01) [Resumo]
Toxicogenetic monitoring in urban cities exposed to different airborne contaminants
(Ecotoxicology and Environmental Safety, 2013-04-01) [Artigo]
Microparticles found in the air may be associated with organic matter that contains several compounds, such as Polycyclic Aromatic Hydrocarbons (PAHs) and nitro-PAHs, and may pose a significant risk to human health, possibly ...
Relationship between gene polymorphisms and DNA damage in morbid obese women
(Environmental and Molecular Mutagenesis, 2011-10-01) [Resumo]
DNA repair gene polymorphism is associated with the genetic basis of atherosclerotic coronary artery disease
(Cardiovascular Pathology, 2011-01-01) [Artigo]
Background: Atherosclerotic coronary artery disease (CAD) is a multifactorial process that appears to be caused by the interaction of environmental risk factors with multiple predisposing genes. It is nowadays accepted ...