Now showing items 31-40 of 834
Diuron-induced rat urinary bladder carcinogenesis: Mode of action and human relevance evaluations using the International Programme on Chemical Safety framework
(Critical Reviews In Toxicology, 2014-05-01) [Artigo]
Diuron, a high volume substituted urea herbicide, induced high incidences of urinary bladder carcinomas and low incidences of kidney pelvis papillomas and carcinomas in rats exposed to high doses (2500 ppm) in a 2-year ...
Diuron metabolites and urothelial cytotoxicity: In vivo, in vitro and molecular approaches
(Toxicology, 2013-12-15) [Artigo]
Diuron is carcinogenic to the rat urinary bladder at high dietary levels. The proposed mode of action (MOA) for diuron is urothelial cytotoxicity and necrosis followed by regenerative urothelial hyperplasia. Diuron-induced ...
Clinical presentation and salivary gland histopathology of paediatric primary Sjogren's syndrome
(Clinical and Experimental Rheumatology, 2011-05-01) [Artigo]
ObjectiveExplore the presentation, diagnostic criteria and exocrine gland histopathology of paediatric primary Sjogren's syndrome (PPSjS).MethodsA case series of 8 children is reported and American-European Consensus Group ...
Expression of 8-oxoguanine Glycosylase in Human Fetal Membranes
(American Journal of Reproductive Immunology, 2014-07-01) [Artigo]
Problem The most common DNA lesion generated by oxidative stress (OS) is 7, 8-dihydro-8-oxoguanine (8-oxoG) whose excision repair is performed by 8-oxoguanine glycosylase (OGG1). We investigated OGG1 expression changes in ...
The central repeat domain 1 of Kaposi's sarcoma-associated herpesvirus (KSHV) latency associated-nuclear antigen 1 (LANA1) prevents cis MHC class I peptide presentation
(Virology, 2011-04-10) [Artigo]
KSHV LANA1, a latent protein expressed during chronic infection to maintain a viral genome, inhibits major histocompatibility complex class I (MHCI) peptide presentation in cis as a means of immune evasion. Through deletional ...
Use of platelet-rich plasma under autogenous onlay bone grafts
(Clinical Oral Implants Research, 2006-12-01) [Artigo]
Objectives: To analyze the healing of autogenous onlay bone grafts in three different situations, focusing on the interface area.Material and methods: Sixteen rabbits underwent autogenous bone graft surgeries in the calvaria. ...
What is your diagnosis? Hepatosplenomegaly in a howler monkey (Alouatta fusca)
(Veterinary Clinical Pathology, 2012-09-01) [Artigo]
Dose-response of diuron [3-(3,4-dichlorophenyl)-1,1-dimethylurea] in the urothelial mucosa of Wistar rats
(Toxicology, 2013-08-20) [Artigo]
Diuron [3-(3,4-dichlorophenyl)-1,1-dimethylurea] is a herbicide that induced urothelial tumors in the urinary bladder of Wistar rats fed 2500. ppm during a long-term study. The currently suggested non-genotoxic mode of ...
Paracoccidioides brasiliensis antigen batches from the same isolate show immunological and biochemical differences
(Mycopathologia, 1996-12-01) [Artigo]
We investigated the occurrence of antigenic and biochemical variability among Paracoccidioides brasiliensis antigen batches prepared according to the same protocol. Initially (experiment 1), we analyzed two antigen lots ...
Histological and immunological reaction of cattle skin to first-instar larvae of Dermatobia hominis
(Medical and Veterinary Entomology, 1996-10-01) [Artigo]
Six cattle that had earlier exposure to Dermatobia hominis were infested experimentally with first-instar larvae of the parasite. Skin biopsies taken at intervals were studied in wax and in plastic sections. The ...