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STORAGE RESULTS IN LOSS of THE ANTIGENOTOXIC PROPERTIES of LENTINULA EDODES (SHIITAKE MUSHROOM) and DEVELOPMENT of IN VIVO GENOTOXICITY
(Journal of Food Biochemistry, 2010-02-01) [Artigo]
In this study, we have investigated the stability of the antigenotoxic properties of dried of Lentinula edodes (Berk.) Singer mushroom powder stored at room and at -20C. Mice were pretreated by gavage for 15 consecutive ...
Influence of diet on oxidative DNA damage, uracil misincorporation and DNA repair capability
(Mutagenesis, 2010-09-01) [Resumo]
The contribution of diet to cancer ranges from 10 to 80%. The low ingestion of antioxidants and enzymatic cofactors involved in DNA repair and methylation reactions and the high ingestion of chemical additives present in ...
Micronucleus cytome assay in potentially malignant lesions and oral cancer
(Oral Diseases, 2010-09-01) [Artigo]
Effects of lycopene, synbiotic and their association on early biomarkers of rat colon carcinogenesis
(Food and Chemical Toxicology, 2010-03-01) [Artigo]
This study evaluated whether a synergy exists for the combined treatment with lycopene and synbiotic on early biomarkers; of colon carcinogenesis. Male Wistar rats received a diet containing 300 mg/kg of lycopene and/or ...
Effects of Helicobacter pylori Infection on the Expressions of Bax and Bcl-2 in Patients with Chronic Gastritis and Gastric Cancer
(Digestive Diseases and Sciences, 2010-01-01) [Artigo]
The aim of the present study is to evaluate the influence of Helicobacter pylori on Bax and Bcl-2 mRNA and protein levels in patients with chronic gastritis and gastric cancer. The study included 217 patients, of which 26 ...
Cell cycle arrest and apoptosis in TP53 subtypes of bladder carcinoma cell lines treated with cisplatin and gemcitabine
(Experimental Biology and Medicine, 2010-07-01) [Artigo]
Currently, the combination of cisplatin and gemcitabine is considered a standard chemotherapeutic protocol for bladder cancer. However, the mechanism by which these drugs act on tumor cells is not completely understood. ...