Now showing items 1-5 of 5
Aberrant crypt foci and colon cancer: comparison between a short- and medium-term bioassay for colon carcinogenesis using dimethylhydrazine in Wistar rats
(Brazilian Journal of Medical and Biological Research, 2002-03-01) [Artigo]
Aberrant crypt foci (ACF) in the colon of carcinogen-treated rodents are considered to be the earliest hallmark of colon carcinogenesis. In the present study the relationship between a short-term (4 weeks) and medium-term ...
No mutations found in exons of TP53, H-RAS and K-RAS genes in liver of male Wistar rats submitted to a medium-term chemical carcinogenesis assay
(Jornal Brasileiro de Patologia e Medicina Laboratorial, 2002-07-01) [Artigo]
O teste padrão para identificar o potencial cancerígeno de compostos químicos é o estudo de longa duração em roedores, não realizado no Brasil. Nosso laboratório estabeleceu um teste alternativo de média duração (ensaio ...
Influence of aqueous extract of Agaricus blazei on rat liver toxicity induced by different doses of diethylnitrosamine
(Journal of Ethnopharmacology, 2002-11-01) [Artigo]
The modifying potential of prior administration of an aqueous extract of the mushroom Agaricus blazei Murrill (Agaricaceae) (Ab) on hepatotoxicity induced by different doses of diethylnitrosamine (DEN) in male Wistar rats ...
Protective action of propolis on the rat colon carcinogenesis
(Teratogenesis Carcinogenesis and Mutagenesis, 2002-01-01) [Artigo]
Propolis is a honeybee product with several biological and therapeutical properties. Its effect on the process of colon carcinogenesis and DNA damage were evaluated in the male Wistar rats using the aberrant crypt foci ...
DNA damage in cytologically normal urothelial cells of patients with a history of urothelial cell carcinoma
(Environmental and Molecular Mutagenesis, 2002-01-01) [Artigo]
In order to determine if patients with a history of previous urothelial cell carcinoma (UCC) but with current normal urinary cytology have DNA damage in urothelial cells, the single-cell gel electrophoresis (comet) assay ...