Now showing items 1-10 of 139
Aberrant crypt foci and colon cancer: comparison between a short- and medium-term bioassay for colon carcinogenesis using dimethylhydrazine in Wistar rats
(Brazilian Journal of Medical and Biological Research, 2002-03-01) [Artigo]
Aberrant crypt foci (ACF) in the colon of carcinogen-treated rodents are considered to be the earliest hallmark of colon carcinogenesis. In the present study the relationship between a short-term (4 weeks) and medium-term ...
Transcriptional Alterations in the SOD2 Gene Is Not Related to the Newborn Obesity Predisposition.
(Environmental And Molecular Mutagenesis, 2014-09-01) [Resumo]
Lycopene activity against chemically induced DNA damage in Chinese hamster ovary cells
(Toxicology in Vitro, 2007-08-01) [Artigo]
Lycopene is a natural pigment synthesized by plants and microorganisms, and it is mainly found in tomatoes. It is an acyclic isomer of P-carotene and one of the most potent antioxidants. Several studies have demonstrated ...
DNA damage in cytologically normal urothelial cells of patients with a history of urothelial cell carcinoma
(Environmental and Molecular Mutagenesis, 2002-01-01) [Artigo]
In order to determine if patients with a history of previous urothelial cell carcinoma (UCC) but with current normal urinary cytology have DNA damage in urothelial cells, the single-cell gel electrophoresis (comet) assay ...
Mutagenic and carcinogenic potential of a textile azo dye processing plant effluent that impacts a drinking water source
(Mutation Research: Genetic Toxicology and Environmental Mutagenesis, 2007-01-10) [Artigo]
Recently a textile azo dye processing plant effluent was identified as one of the sources of mutagenic activity detected in the Cristais River, a drinking water source in Brazil [G.A. Umbuzeiro, D.A. Roubicek, C.M. Rech, ...
No mutations found in the exon 2 of p16 INK4a and K-ras
(Oral Oncology, 2009-07-01) [Resumo]
DNA damage and its relationship with morbid obesity.
(Environmental and Molecular Mutagenesis, 2011-10-01) [Resumo]
Farming technology, biochemistry characterization, and protective effects of culinary-medicinal mushrooms Agaricus brasiliensis S. Wasser et al. and Lentinus edodes (Berk.) Singer: Five years of research in Brazil
(International Journal of Medicinal Mushrooms, 2005-07-04) [Artigo]
The biotechnology, biochemical characterization, and protective effects of the himematsutake and shiitake mushrooms were studied for the Thematic Project, from 1998 to 2003. A new species, Agaricus Brasiliens is Wasser et ...
Genotoxicity of cigarette smoking in maternal and newborn lymphocytes
(Mutation Research: Genetic Toxicology and Environmental Mutagenesis, 2009-09-01) [Artigo]
Tobacco smoke contains a large number of substances known to induce DNA damage and to be hazardous to human health. Several reviews and meta-analyses have reported an association between maternal or paternal smoking habits ...
No relationship between subchronic fluoride intake and DNA damage in Wistar rats
(Caries Research, 2004-01-01) [Artigo]
Fluoride has been widely used in dentistry because it is an effective caries prophylactic agent. However, excess fluoride may represent a hazard to human health, especially by causing injury on the genetic apparatus. ...