Now showing items 1-10 of 1053
Burdock (Arctium lappa L.) root attenuates preneoplastic lesion development in a diet and thioacetamide-induced model of steatohepatitis-associated hepatocarcinogenesis
(Environmental Toxicology, 2020-04-01) [Artigo]
Nonalcoholic steatohepatitis (NASH) is considered growing risk factor for hepatocellular carcinoma development in high-income countries. Diet- and chemically induced rodent models have been applied for the translational ...
Loss of 5 '-Methylthioadenosine Phosphorylase (MTAP) is Frequent in High-Grade Gliomas; Nevertheless, it is Not Associated with Higher Tumor Aggressiveness
(Cells, 2020-02-01) [Artigo]
The 5'-methylthioadenosine phosphorylase (MTAP) gene is located in the chromosomal region 9p21. MTAP deletion is a frequent event in a wide variety of human cancers; however, its biological role in tumorigenesis remains ...
Prolapso de glândula de terceira pálpebra em cäes: Avaliação cito e histopatológica
(Archives of Veterinary Science, 2007-12-01) [Artigo]
The present experiment was carried out in ten animals with third eyelid prolapsed gland. All of the prolapsed glands were surgically excised. The age of the dogs ranged from two month to ten years old, and the breeds were ...
Medium-term tongue carcinogenesis assays: A comparative study between 4-nitroquinoline 1-oxide (4NQO)-induced rat and dimethylbenzanthracene (DMBA)-induced hamster carcinogenesis
(Journal of Experimental Animal Science, 2006-12-12) [Artigo]
The most used animal models in oral cancer research are the hamster treated by dimethylbenzanthracene (DMBA), and the rat treated by 4-nitroquinoline 1-oxide (4NQO). The purpose of this study was to compare the DMBA-induced ...
Tumor microenvironmental genomic alterations in juvenile nasopharyngeal angiofibroma
(Head and Neck: Journal for the Sciences and Specialties of the Head and Neck, 2012-04-01) [Artigo]
Background To better characterize the pathophysiology of juvenile nasopharyngeal angiofibroma (JNA), endothelial and stromal cells were evaluated by genomic imbalances in association with transcript expression levels of ...
Câncer de pulmão: histologia, estádio, tratamento e sobrevida
(Jornal Brasileiro de Pneumologia, 2008-08-01) [Artigo]
OBJETIVO: Analisar os principais tipos histológicos, estádio, tratamento e sobrevida dos portadores de câncer de pulmão. MÉTODOS: Estudo retrospectivo a partir da análise dos prontuários de pacientes acompanhados no Hospital ...
DNA damage in lymphocytes and buccal mucosa cells of children with malignant tumours undergoing chemotherapy
(Clinical and Experimental Medicine, 2008-06-01) [Artigo]
The aim of the present study was to evaluate DNA damage (micronucleus) in cytokinesis-blocked lymphocytes and exfoliated buccal mucosa cells from children with malignant tumours and under chemotherapy. Micronucleated cells ...
The role of p53 protein and TP53 gene during rat oral carcinogenesis induced by 4NQO
(Oral Oncology, 2009-07-01) [Artigo]
Cutaneous myxosarcoma in a Syrian hamster (Mesocricetus auratus)
(Semina: Ciências Agrárias, 2011-01-01) [Artigo]
The pathological findings in a 2-years-old Syrian hamster (Mesocricetus auratus) with a cutaneous myxosarcoma are described. Grossly, there was a large cutaneous mass in the right cervical region. Microscopical evaluation ...
Barium Enema Revisited in the Workup for the Diagnosis of Hirschsprung's Disease
(Journal of pediatric gastroenterology and nutrition, 2019-04-01) [Artigo]
OBJECTIVE: To analyse the diagnostic capacity of barium enema (BE) in the diagnostic investigation for Hirschsprung's disease (HD) was analyzed for transition zone (TZ) identification and rectosigmoid index (RSI) ≤1.0 ...