Now showing items 1-6 of 6
Genotoxicity of cigarette smoking in maternal and newborn lymphocytes
(Mutation Research: Genetic Toxicology and Environmental Mutagenesis, 2009-09-01) [Artigo]
Tobacco smoke contains a large number of substances known to induce DNA damage and to be hazardous to human health. Several reviews and meta-analyses have reported an association between maternal or paternal smoking habits ...
In vivo genotoxicity evaluation of a treated urban sewage sludge sample
(Mutation Research: Genetic Toxicology and Environmental Mutagenesis, 2009-05-31) [Artigo]
Tons of sludge is produced daily in sewage treatment plants of large cities, causing an enormous disposal problem. Because recycling has been proposed to mitigate the Situation, the potential adverse health effects of the ...
Genetic biomonitoring of an urban population exposed to mutagenic airborne pollutants
(Environment International, 2009-10-01) [Artigo]
Biomonitoring studies have increased as a consequence of risks and effects to human health on exposure to environmental contaminants, mainly air pollutants. Genetic biomarkers are useful tools for the early assessment of ...
Evaluation of the antigenotoxicity of polysaccharides and beta-glucans from Agaricus blazei, a model study with the single cell gel electrophoresis/Hep G2 assay
(Journal of Food Composition and Analysis, 2009-11-01) [Artigo]
The mushroom Agaricus blazei (Agaricus brasiliensis) has been drawing attention because of its medicinal properties. Among its isolated compounds, special consideration is given to beta-glucans, which are cell wall ...
Salinomycin efficiency assessment in non-tumor (HB4a) and tumor (MCF-7) human breast cells
(Naunyn-schmiedebergs Archives Of Pharmacology, 2016-06-01) [Artigo]
The search for anticancer drugs has led researchers to study salinomycin, an ionophore antibiotic that selectively destroys cancer stem cells. In this study, salinomycin was assessed in two human cell lines, a breast ...
Cell cycle kinetics, apoptosis rates, DNA damage and TP53 gene expression in bladder cancer cells treated with allyl isothiocyanate (mustard essential oil)
(Mutation Research: Fundamental and Molecular Mechanisms of Mutagenesis, 2014-04-01) [Artigo]
Allyl isothiocyanate (AITC) is present in plants of the cruciferous family and is abundant in mustard seed. Due to its high bioavailability in urine after ingestion, AITC has been considered a promising antineoplastic agent ...