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Genomic instability in blood cells is able to predict the oral cancer risk: an experimental study in rats
(Journal of Molecular Histology, 2008-10-01) [Artigo]
This study was undertaken to investigate the genomic instability on blood cells during 4-nitroquinoline 1-oxide (4NQO)-induced rat tongue carcinogenesis by means of single cell gel (comet) and micronucleus assays. Male ...
DNA methylation patterns in bladder cancer and washing cell sediments: a perspective for tumor recurrence detection
(BMC Cancer, 2008-08-14) [Artigo]
Background: Epigenetic alterations are a hallmark of human cancer. In this study, we aimed to investigate whether aberrant DNA methylation of cancer-associated genes is related to urinary bladder cancer recurrence.Methods: ...